鼻用糖皮质激素治疗变应性鼻结膜炎的疗效分析  

Analysis of the Efficacy of Nasal Glucocorticoids in the Treatment of Aller⁃gic Rhinoconjunctivitis

作　　者：金泽奇 沈骏杰 陈进 JIN Zeqi;SHEN Junjie;CHEN Jin(Department of Otorhinolaryngology,Wuzhong District Changqiao People's Hospital,Suzhou,Jiangsu Province,215000 China;Department of Ophthalmology,Wuzhong District Changqiao People's Hospital,Suzhou,Jiangsu Prov-ince,215000 China)

机构地区：[1]苏州市吴中区长桥人民医院耳鼻喉科,江苏苏州215000 [2]苏州市吴中区长桥人民医院眼科,江苏苏州215000

出　　处：《系统医学》2024年第3期109-111,115,共4页Systems Medicine

摘　　要：目的研究鼻用糖皮质激素治疗变应性鼻结膜炎的疗效。方法选取2023年2—10月苏州市吴中区长桥人民医院接受治疗的160例变应性鼻结膜患者为研究对象,采用信封法分为对照组和研究组,各80例。对照组给予氟米龙滴眼液治疗,研究组给予氟米龙滴眼液联合雷诺考特治疗。对比两组患者治疗后的临床效果、眼部评分、鼻部评分及不良反应情况。结果研究组治疗总有效率高于对照组(87.50%vs 75.00%),差异有统计学意义(χ^(2)=4.103,P<0.05)。治疗后,两组各项症状评分均明显改善,差异有统计学意义(P均<0.05)。且研究组鼻部评分(2.75±0.37)分、眼部评分(1.52±0.57)分,均低于对照组,差异有统计学意义(t=15.894、12.505,P均<0.05)。两组不良反应总发生率比较,差异无统计学意义(χ^(2)=0.207,P>0.05)。结论鼻用激素治疗变应性鼻结膜炎具有显著的效果,同时可改善患者鼻、眼部情况。Objective To study the efficacy of nasal glucocorticoids in the treatment of allergic rhinoconjunctivitis.Methods A total of 160 patients with allergic nasoconjunctival receiving treatment in Changqiao People's Hospital of Wuzhong District at Suzhou City from February to October 2023 were selected as the research object,and divided into the control group and the study group using envelope method,with 80 cases in each group.The control group was treated with flumiron eye drops,and the study group was treated with flumiron eye drops combined with renocott.The clinical effects,ocular scores,nasal scores and adverse reactions were compared between the two groups after treat⁃ment.Results The total effective rate of the study group was higher than that of the control group(87.50%vs 75.00%),and the difference was statistically significant(χ^(2)=4.103,P<0.05).After treatment,all symptom scores of the two groups were significantly improved,and the differences were statistically significant(both P<0.05).The nasal score(2.75±0.37)points and ocular score(1.52±0.57)points of the study group were lower than those of the control group,and the differences were statistically significant(t=15.894,12.505,both P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(χ^(2)=0.207,P>0.05).Conclusion Nasal hormone treatment of allergic rhinoconjunctivitis has a remarkable effect,and can improve the nasal and ocular conditions of patients.

关 键 词：鼻用糖皮质激素 变应性鼻炎 变应性结膜炎 变应性鼻结膜炎 氟米龙 雷诺考特 临床疗效 

分 类 号：R765[医药卫生—耳鼻咽喉科]