消癥止痛散外敷治疗气滞血瘀型体表恶性肿瘤伴有癌性疼痛的疗效观察  

Observation on the therapeutic effect of external application of Xiaozheng Zhitong Powder in the treatment of malignant tumors with cancerous pain of Qi stagnation and blood stasis type on the body surface

作　　者：余敏敏 刘梅芬 石玲[3] YU Minmin;LIU Meifen;SHI Ling(Department of Pharmacy,Jiujiang Traditional Chinese Medicine Hospital,Jiangxi Province,Jiujiang332000,China;Department of Oncology,Jiujiang Traditional Chinese Medicine Hospital,Jiangxi Province,Jiujiang332000,China;Department of Oncology,No.1 People's Hospital,Jiangxi Province,Jiujiang332000,China)

机构地区：[1]江西省九江市中医医院药剂科,江西九江332000 [2]江西省九江市中医医院肿瘤科,江西九江332000 [3]江西省九江市第一人民医院肿瘤科,江西九江332000

出　　处：《中国当代医药》2024年第10期100-104,共5页China Modern Medicine

基　　金：江西省中医药管理局科技计划项目(2023B0685)。

摘　　要：目的探讨消癥止痛散外敷治疗气滞血瘀型体表恶性肿瘤伴有癌性疼痛的效果。方法选取2022年5月至2023年5月九江市中医医院收治的60例气滞血瘀型体表恶性肿瘤伴有癌性疼痛患者作为研究对象,按照随机数字表法分为对照组(30例)和观察组(30例)。对照组采用盐酸羟考酮缓释片治疗,观察组在对照组的基础上加用消癥止痛散外敷治疗,两组均连续治疗7 d。比较两组的止痛效果、疼痛程度、爆发痛的次数、气滞血瘀症状评分、羟考酮缓释片日均使用剂量、生活质量和不良反应。结果观察组止痛缓解率高于对照组,差异有统计学意义(P<0.05);两组治疗前痛程度、爆发痛的次数、气滞血瘀症状评分比较,差异无统计学意义(P>0.05);两组治疗后疼痛程度、爆发痛的次数、气滞血瘀症状评分低于治疗前,差异有统计学意义(P<0.05);观察组治疗后疼痛程度、爆发痛的次数、气滞血瘀症状评分低于对照组,差异有统计学意义(P<0.05);两组治疗第1天羟考酮缓释片日均使用剂量比较,差异无统计学意义(P>0.05);两组治疗第7天羟考酮缓释片日均使用剂量低于治疗前,差异有统计学意义(P<0.05);观察组治疗第7天羟考酮缓释片日均使用剂量低于对照组,差异有统计学意义(P<0.05);观察组生活质量优于对照组,差异有统计学意义(P<0.05);两组不良反应总发生率比较,差异无统计学意义(P>0.05)。结论气滞血瘀型体表恶性肿瘤伴有癌性疼痛患者应用消癥止痛散外敷止痛效果较佳,可减轻盐酸羟考酮缓释片用量,减少爆发性痛发作次数,利于缓解气滞血瘀症状,改善患者生活质量,且安全可靠。Objective To explore the curative effect of external application of Xiaozheng Zhitong Powder in the treatment of malignant tumors with cancerous pain of Qi stagnation and blood stasis type on the body surface.Methods A total of 60 patients with malignant tumors with cancerous pain of Qi stagnation and blood stasis type on the body surface admitted to Jiujiang Traditional Chinese Medicine Hospital from May 2022 to May 2023 were selected as the study objects,and they were divided into control group(30 cases)and observation group(30 cases)according to random number table method.The control group was treated with Oxycodone Hydrochloride Sustained-release Tablets,and the observation group was treated with Xiaozheng Zhitong Powder based on control group,both groups were treated continuously for 7 d.The analgesic effect,pain degree,frequency of pain outbreak,symptom score of Qi stagnation and blood stasis,daily dose of Oxycodone Hydrochloride Sustained-release Tablets,quality of life and adverse reactions were compared between the two groups.Results The analgesic remission rate of observation group was higher than that of control group,the difference was statistically significant(P<0.05).There was no significant difference between the two groups in pain degree,frequency of pain outbreak and symptom score of Qi stagnation and blood stasis before treatment(P>0.05).The pain degree,frequency of pain outbreak and the symptom score of Qi stagnation and blood stasis after treatment were lower than those before treatment,and the differences were statistically significant(P<0.05).After treatment,the pain degree,frequency of pain outbreak and the symptom score of Qi stagnation and blood stasis in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).There was no significant difference in the daily dose of Oxycodone Hydrochloride Sustained-release Tablets between the two groups on the 1 d of treatment(P>0.05).The daily dose of Oxycodone Hydrochloride Sustained-r

关 键 词：体表恶性肿瘤 癌性疼痛 气滞血瘀型 消癥止痛散外敷 

分 类 号：R441.1[医药卫生—诊断学]