四磨汤与胃复安对危重症患者胃潴留的治疗效果研究  

Study on effect of Simo decoction and metoclopramide in the treatment of critically ill patients with gastric retention

作　　者：邓海芳 温振杰 刘建凌 明建青 DENG Hai-fang;WEN Zhen-jie;LIU Jian-ling(The Affiliated Sixth Hospital of Guangzhou Medical University(the People's Hospital in Qingyuan City),Qingyuan 511518,China)

机构地区：[1]广州医科大学附属第六医院(清远市人民医院),511518

出　　处：《中国现代药物应用》2024年第6期144-146,共3页Chinese Journal of Modern Drug Application

基　　金：广东省中医药管理局面上项目(项目编号:20201408),项目名称:四磨汤与胃复安对危重症患者胃潴留的效果研究

摘　　要：目的探讨四磨汤与胃复安对危重症患者胃潴留的治疗效果。方法选取重症加强护理病房(ICU)收治的80例危重症合并胃潴留患者作为研究对象,依据随机纸片法分为四磨汤组和胃复安组,每组40例。比较两组患者的治疗效果、入院急性生理学及慢性健康状况评分系统Ⅱ(APACHE-Ⅱ)评分、入院序贯器官衰竭估计评分(SOFA)、ICU住院时间、机械通气时间、并发症发生率。结果胃复安组患者的总有效率为80.00%,与四磨汤组的87.50%比较,差异无统计学意义(P>0.05)。胃复安组患者的入院APACHE-Ⅱ评分、入院SOFA评分、ICU住院时间、机械通气时间、并发症发生率分别为(23.65±5.62)分、(9.87±1.23)分、(10.02±4.40)d、(70.68±6.72)h、22.50%,与四磨汤组的(24.18±6.07)分、(9.62±1.98)分、(11.90±4.84)d、(72.37±6.53)h、15.00%比较,差异无统计学意义(P>0.05)。结论四磨汤与胃复安在危重症患者胃潴留中的治疗效果相当。Objective To explore the effect of Simo decoction and metoclopramide in the treatment of critically ill patients with gastric retention.Methods 80 cases of critically ill patients with gastric retention in intensive care unit(ICU)were selected as subjects,and were randomly divided into Simo decoction group and metoclopramide group,with 40 cases in each group.Comparison was made on therapeutic effect,Acute Physiology and Chronic Health EvaluationⅡ(APACHE-Ⅱ)score on admission,sequential organ failure assessment(SOFA)on admission,length of ICU stay,mechanical ventilation,complication rate between the two group.Results The total effective rate of metoclopramide group was 80.00%,which was not statistically significant compared with 87.50%in Simo decoction group(P>0.05).In metoclopramide group,the APACHE-Ⅱscore on admission,SOFA score on admission,length of ICU stay,mechanical ventilation time and complication rate were(23.65±5.62)points,(9.87±1.23)points,(10.02±4.40)d,(70.68±6.72)h and 22.50%,and those in the Simo decoction group were(24.18±6.07)points,(9.62±1.98)points,(11.90±4.84)d,(72.37±6.53)h and 15.00%,and the difference between the two groups was not statistically significant(P>0.05).Conclusion The effect of Simo decoction and metoclopramide in the treatment of gastric retention in critically ill patients is comparable.

关 键 词：四磨汤 胃复安 危重症 胃潴留 

分 类 号：R278[医药卫生—中医学]