血运重建在急性心肌梗死患者急诊救治中的应用效果  

Application Effect of Revascularization in Emergency Treatment of Patients with Acute Myocardial Infarction

作　　者：熊操 XIONG Cao(Xiamen Fifth Hospital,Xiamen 361000,China)

机构地区：[1]厦门市第五医院,福建厦门361000

出　　处：《中外医学研究》2024年第5期27-30,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探讨血运重建在急性心肌梗死(acute myocardial infarction,AMI)患者急诊救治中的应用效果。方法:选取2021年7月—2022年9月厦门市第五医院收治的109例AMI患者作为研究对象,依据治疗方案的不同将其分为研究组(55例)和对照组(54例)。对照组仅行内科药物治疗,研究组在内科药物治疗的同时在相应治疗时间窗内实施血运重建术。比较两组治疗前、治疗3个月心功能指标、心肌微循环指标、心脏胶原重塑指标、住院期间不良心血管事件发生情况。结果:治疗3个月,两组左室舒张末期内径(left ventricular end-diastolic diameter,LVEDD)、左室收缩末期内径(left ventricular end-systolic diameter,LVESD)、左室后壁舒张末期厚度(left ventricular posterior wall diastolic,LVPWD)、室间隔厚度(interventricular septal thickness,IVST)均较治疗前明显降低,左室射血分数(left ventricular ejection fraction,LVEF)较治疗前明显升高,且研究组LVEDD、LVESD、LVPWD、IVST低于对照组,LVEF高于对照组,差异有统计学意义(P<0.05)。治疗3个月,两组心肌微循环指标较治疗前明显升高,且研究组高于对照组,差异有统计学意义(P<0.05)。治疗3个月,两组心脏胶原重塑指标较治疗前明显升高,且研究组高于对照组,差异有统计学意义(P<0.05)。研究组不良心血管事件发生率为3.64%,明显低于对照组的16.67%,差异有统计学意义(P<0.05)。结论:AMI患者接受血运重建治疗,可改善心功能、心肌微循环状况,抑制心室重塑,降低不良心血管事件发生风险。Objective:To investigate the application effect of revascularization in the emergency treatment of patients with acute myocardial infarction(AMI).Method:A total of 109 AMI patients admitted to Xiamen Fifth Hospital from July 2021 to September 2022 were selected as the study objects,and they were divided into study group(55 cases)and control group(54 cases)according to different treatment plans.The control group was treated with medical drugs only,and the study group was treated with medical drugs and revascularization in the corresponding treatment time window.Cardiac function indexes,myocardial microcirculation indexes,cardiac collagen remodeling indexes before treatment and treatment for 3 months and adverse cardiovascular events during hospitalization were compared between the two groups.Result:Treatment for 3 months,the left ventricular end-diastolic diameter(LVEDD),left ventricular end-systolic diameter(LVESD),left ventricular posterior wall diastolic(LVPWD)and interventricular septal thickness(IVST)of both groups were significantly decreased compared with before treatment,and left ventricular ejection fraction(LVEF)were significantly increased compared with before treatment,the LVEDD,LVESD,LVPWD and IVST of the study group were lower than those of the control group,and LVEF of the study group was higher than that of the control group,the differences were statistically significant(P<0.05).Treatment for 3 months,myocardial microcirculation indexes in both groups were significantly higher than before treatment,and the indexes in the study group were higher than those in the control group,the differences were statistically significant(P<0.05).Treatment for 3 months,the cardiac collagen remodeling indexes in both groups were significantly higher than before treatment,and the indexes in the study group were higher than those in the control group,the differences were statistically significant(P<0.05).The incidence of adverse cardiovascular events in the study group was 3.64%,significantly lower than 16.67% in the

关 键 词：血运重建 急性心肌梗死 心肌微循环 胶原重塑 

分 类 号：R542.22[医药卫生—心血管疾病]