缩宫素联合间苯三酚在低宫颈评分足月胎膜早破产妇分娩中的应用  

Application of Oxytocin Combined with Phloroglucinol in the Delivery of Full Term Lying-in Woman with Premature Rupture of Membranes with Low Cervical Score

作　　者：徐莉 严丽慧 谢利萍[1] XU Li;YAN Lihui;XIE Liping(Haining People's Hospital,Haining 314400,China;不详)

机构地区：[1]海宁市人民医院,浙江海宁314400

出　　处：《中外医学研究》2024年第7期46-50,共5页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:观察缩宫素联合间苯三酚在低宫颈评分足月胎膜早破(PROM)产妇分娩中的应用。方法:回顾性选取2020年9月—2022年4月海宁市人民医院妇产科收治的160例低宫颈评分足月PROM产妇的临床资料。根据不同治疗方法将其分为对照组、观察1组、观察2组、观察3组,各40例。对照组单纯使用缩宫素,观察组使用缩宫素联合间苯三酚,观察1组于出现规律宫缩时静脉缓慢推注间苯三酚注射液80 mg;观察2组在宫口开大2~3 cm时静脉缓慢推注间苯三酚注射液80 mg;观察3组在进入活跃期、宫口开大≥5 cm时静脉缓慢推注间苯三酚注射液80 mg。比较四组分娩方式、宫口扩张速度、宫口开全时间、产后出血情况、产后并发症及新生儿不良事件。结果:观察2组、观察3组阴道分娩率高于对照组,差异有统计学意义(P<0.05)。观察2组的宫口扩张速度大于对照组与观察1组,宫口开全时间短于对照组与观察1组,差异有统计学意义(P<0.05)。观察1组、观察2组的产后2 h出血量少于对照组与观察3组,差异有统计学意义(P<0.05)。四组产后尿潴留、产褥感染、新生儿不良事件发生率比较,差异无统计学意义(P>0.05)。结论:缩宫素联合间苯三酚在低宫颈评分足月PROM产妇分娩中的应用效果优于单纯使用缩宫素,在宫口开大2~3 cm时静脉缓慢推注间苯三酚80 mg的效果最优,可获得较高的阴道分娩率,且可加快宫口扩张速度、缩短宫口开全时间,减少产后出血量,且不增加产后尿潴留、产褥感染、新生儿不良事件的发生率,有效性与安全性兼具。Objective:To observe the application of Oxytocin combined with Phloroglucinol in the delivery of full term lyingin woman with premature rupture of membranes(PROM)with low cervical score.Method:The clinical data of 160 full-term PROM lying-in woman with low cervical score who were admitted to the Obstetrics and Gynecology Department of Haining People's Hospital from September 2020 to April 2022 were retrospectively selected.According to different treatment methods,the patients were divided into control group,observation group 1,observation group 2 and observation group 3,with 40 cases in each group.The control group was treated with Oxytocin alone,and the observation group was treated with Oxytocin combined with Phloroglucinol.Observation group 1 was given Phloroglucinol Injection 80 mg intravenously slowly when regular contractions occurred.Observation group 2 injected Phloroglucinol 80 mg slowly when the uterine orifice was opened 2-3 cm wider.Observation group 3 injected Phloroglucinol Injection 80 mg intravenously slowly when entering the active phase and the uterine opening was≥5 cm.Methods of delivery,uterine dilation speed,uterine opening time,postpartum hemorrhage condition,postpartum complications and neonatal adverse events were compared among the four groups.Result:The vaginal delivery rate of observation group 2 and observation group 3 was higher than that of control group,and the difference was statistically significant(P<0.05).The dilation rate of uterine orifice in observation group 2 was higher than that in control group and observation group 1,and the total opening time of uterine orifice in observation group 2 was shorter than that in control group and observation group 1,the differences were statistically significant(P<0.05).The postpartum 2 h blood loss volume in observation group 1 and observation group 2 was less than that in control group and observation group 3,and the difference was statistically significant(P<0.05).There were no significant differences in the incidences of postpartum ur

关 键 词：缩宫素 间苯三酚 低宫颈评分 胎膜早破 分娩 

分 类 号：R714.433[医药卫生—妇产科学]