CT定位下硬通道微创穿刺引流术联合尿激酶灌注治疗老年高血压脑出血患者的效果  

Effect of Hard Channel Minimally Invasive Puncture and Drainage Surgery Under CT Positioning Combined with Urokinase Perfusion in the Treatment of Elderly Patients with Hypertensive Cerebral Hemorrhage

作　　者：张海坡[1] 何建军[1] 佘晓春[1] ZHANG Haipo;HE Jianjun;SHE Xiaochun(Rudong County People's Hospital,Rudong 226400,China;不详)

机构地区：[1]如东县人民医院,江苏如东226400

出　　处：《中外医学研究》2024年第9期44-47,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:分析CT定位下硬通道微创穿刺引流术联合尿激酶灌注治疗老年高血压脑出血患者的效果。方法:选取2018年3月—2023年3月如东县人民医院收治的102例老年高血压脑出血患者。根据入院顺序进行编号,利用最新统计学软件生成随机序列后将其分为对照组(51例)和观察组(51例)。对照组给予保守治疗,观察组在对照组基础上给予CT定位下硬通道微创穿刺引流术联合尿激酶灌注治疗。比较两组治疗1周后临床疗效,治疗前及治疗1周后血管内皮功能、预后及生活质量,并发症。结果:观察组治疗总有效率高于对照组,差异有统计学意义(P<0.05)。治疗1周后,观察组一氧化氮(nitric oxide,NO)水平高于对照组,内皮素-1(endothelin-1,ET-1)水平低于对照组,差异有统计学意义(P<0.05)。治疗1周后,观察组改良Rankin量表(modified Rankin scale,mRS)评分低于对照组,改良Barthel指数(modified Barthel index,MBI)评分高于对照组,差异有统计学意义(P<0.05)。观察组并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论:对于老年高血压脑出血患者采取CT定位下硬通道微创穿刺引流术联合尿激酶灌注治疗效果显著,有利于改善血管内皮功能,提高预后及生活质量水平,并降低并发症发生率。Objective:To analyze the effect of hard channel minimally invasive puncture and drainage surgery under CT positioning combined with Urokinase perfusion in the treatment of elderly patients with hypertensive cerebral hemorrhage.Method:A total of 102 elderly patients with hypertensive cerebral hemorrhage treated in Rudong County People's Hospital from March 2018 to March 2023 were selected.The patients were numbered according to the order of admission,and were divided into control group(51 cases)and observation group(51 cases)after generating random sequence using the latest statistical software.The control group was given conservative treatment,and the observation group was given hard channel minimally invasive puncture and drainage surgery under CT positioning combined with Urokinase perfusion on the basis of the control group.The clinical efficacy after 1 week of treatment,vascular endothelial function,prognosis,quality of life before and after 1 week of treatment and complications were compared between the two groups.Result:The treatment total effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).After 1 week of treatment,the level of nitric oxide(NO)in the observation group was higher than that in the control group,and endothelin-1(ET-1)in the observation group was lower than that in the control group,and the differences were statistically significant(P<0.05).After 1 week of treatment,the modified Rankin scale(mRS)score of the observation group was lower than that of the control group,and the modified Barthel index(MBI)score of the observation group was higher than that of control group,and the differences were statistically significant(P<0.05).The incidence of complications in the observation group was lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion:For elderly patients with hypertensive intracerebral hemorrhage,hard channel minimally invasive puncture and drainage surgery

关 键 词：CT 定位 硬通道微创穿刺引流术 尿激酶灌注 老年 高血压脑出血 

分 类 号：R651.12[医药卫生—外科学]