磁共振梯度回波T_(2)^(*)加权成像参数优化在急性缺血性脑卒中患者中的临床应用价值探讨  

Exploration on the clinical application value of optimization of magnetic resonance gradient echo T_(2)^(*) weighted imaging sequence parameters in patients with acute ischemic stroke

作　　者：李燕华 杨维珍 陈鹏 李瑞雄 严业静 王天照 LI Yanhua;YANG Weizhen;CHEN Peng;LI Ruixiong;YAN Yejing;WANG Tianzhao(Department of Medical Imaging,the People's Hospital of Wuzhou,Guangxi 543003,China;Department of Medical Imaging,Guangxi International Zhuang Medicine Hospital,Nanning 530022,China)

机构地区：[1]梧州市人民医院医学影像科,广西543003 [2]广西国际壮医医院医学影像科,南宁530022

出　　处：《中国临床新医学》2024年第3期328-332,共5页CHINESE JOURNAL OF NEW CLINICAL MEDICINE

基　　金：梧州市科学研究与技术开发计划项目(编号:201702084)。

摘　　要：目的探讨磁共振梯度回波T_(2)^(*)加权成像(GRE-T_(2)^(*)WI)参数优化在急性缺血性脑卒中(AIS)患者中的临床应用价值。方法选取2017年6月至2018年12月在梧州市人民医院就诊的50例AIS患者,男38例,女12例,年龄41~92(65.50±5.90)岁。利用四组参数对每例患者进行GRE-T_(2)^(*)WI检查,并获得四组图像:A组为对照组,B组在A组的基础上减少矩阵、激励次数(NEX)和重复时间(TR),C组在B组的基础上采用并行采集技术并减少TR及回波时间(TE),D组在C组的基础上进一步减少TR、TE和矩阵。对四组图像的扫描时间、图像质量评分、信噪比(SNR)及对比噪声比(CNR)进行比较。结果A组、B组、C组、D组扫描时间分别为81 s、40 s、15 s和11 s。四组参数图像质量评分、SNR、CNR差异有统计学意义(P<0.05)。A组、B组、C组、D组图像质量评分分别为(3.56±0.28)分、(3.34±0.34)分、(3.00±0.32)分、(1.68±0.40)分。C组与D组图像质量评分差异有统计学意义(P<0.05),C组与A组、B组图像质量评分差异无统计学意义(P>0.05)。D组SNR最高,C组与A组、B组SNR差异有统计学意义(P<0.05),C组与D组SNR差异无统计学意义(P>0.05)。C组CNR最高,C组与A组、D组CNR差异无统计学意义(P>0.05),C组与B组CNR差异有统计学意义(P<0.05)。结论通过采用并行采集技术以及对矩阵、NEX、TR、TE等参数的适当减少后,GRE-T_(2)^(*)WI扫描时间明显缩短,图像质量达到诊断要求,在临床上对AIS患者诊治具有较大的应用价值。Objective To explore the clinical application value of optimization of magnetic resonance gradient echo T_(2)^(*) weighted imaging(GRE-T_(2)^(*)WI)sequence parameters in patients with acute ischemic stroke(AIS).Methods A total of 50 AIS patients were selected from the People's Hospital of Wuzhou during June 2017 and December 2018,including 38 males and 12 females,aged 41 to 92(65.50±5.90)years.GRE-T_(2)^(*)WI examination was performed on each patient using four parameters,and four groups of images were obtained.Group A was the control group,and group B had the reduced matrix,number of excitation(NEX)and time of repetition(TR)on the basis of group A,and group C adopted parallel acquisition technique and had the reduced NEX,TR and echo time(TE)on the basis of group B,and group D had the further reduced TR,TE and matrix on the basis of group C.The scanning time,image quality score,signal-to-noise ratio(SNR)and contrast-to-noise ratio(CNR)of the images were compared among the four groups.Results The scanning time in group A,group B,group C and group D was 81 seconds,40 seconds,15 seconds and 11 seconds,respectively.There were significant differences in the image quality scores,SNR and CNR of the parameters among the four groups(P<0.05).The image quality scores in group A,group B,group C and group D were(3.56±0.28)points,(3.34±0.34)points,(3.00±0.32)points and(1.68±0.40)points,respectively.There were significant differences in the image quality scores between group C and group D(P<0.05).There were no significant differences in the image quality scores between group C and group A as well as between group C and group B(P>0.05).Group D had the highest level of SNR,and there were significant differences in the levels of SNR between group C and group A as well as between group C and group B(P<0.05).There was no significant difference in the level of SNR between group C and group D(P>0.05).Group C had the highest level of CNR,and there were no significant differences in the levels of CNR between group C and group A as

关 键 词：急性缺血性脑卒中 磁共振 梯度回波T_(2)^(*)加权成像 参数优化 图像质量 

分 类 号：R445.2[医药卫生—影像医学与核医学]