生物催化技术在化学制药中的应用  

Application of Biocatalytic Technology in Chemical Pharmaceuticals

作　　者：刘霞 常华 伊慧敏 Liu Xia;Chang Hua;Yi Huimin(Weiqida Pharmaceutical Co.,Ltd.,China National Pharmaceutical Group,Shanxi,037300)

机构地区：[1]国药集团威奇达药业有限公司,山西037300

出　　处：《当代化工研究》2024年第6期117-119,共3页Modern Chemical Research

摘　　要：生物催化技术是一种利用酶或微生物进行化学反应的技术,通过生物体内的天然催化系统实现选择性、高效和温和的化学合成或分解。在有机合成、制药、食品工业和环境保护等领域,生物催化技术展现出高度优越性。其优势包括高选择性、高效催化、温和反应条件、对复杂底物的容忍度、可再生性和环境友好。特别在制药领域,裂解酶、氧化酶、还原酶和转移酶等酶催化技术被广泛应用,提供了高效、选择性和可持续的药物合成解决方案。随着对生物催化技术的深入理解和生物技术的发展,其未来应用前景广阔。Biocatalysis technology is a technology that utilizes enzymes or microorganisms to carry out chemical reactions,achieving selec-tive,efficient,and mild chemical synthesis or decomposition through natural catalytic systems within the organism.In the fields of organic synthesis,pharmaceuticals,food industry,and environmental protection,biocatalytic technology has shown high superiority.Its advantages include high selec-tivity,efficient catalysis,mild reaction conditions,tolerance for complex substrates,renewability,and environmental friendliness.Especially in the pharmaceutical field,enzyme catalytic technologies such as lyases,oxidases,reductases,and transferases are widely used,providing efficient,selec-tive,and sustainable drug synthesis solutions.With a deeper understanding of biocatalytic technology and the development of biotechnology,its fu-ture application prospects are broad.

关 键 词：生物催化技术 酶催化技术 化学制药 具体应用 

分 类 号：Q81[生物学—生物工程]