Photocatalytic synthesis of small-molecule drugs by porous framework materials  

作　　者：Yingying Zhao Jiangpei Yuan Lei Zhu Yu Fang 

机构地区：[1]State Key Laboratory of Chemo/Bio-Sensing and Chemometrics,College of Chemistry and Chemical Engineering,Hunan University,Changsha 410082,China [2]Innovation Institute of Industrial Design and Machine Intelligence Quanzhou-Hunan University,Quanzhou 362801,China

出　　处：《Chinese Chemical Letters》2024年第3期52-65,共14页中国化学快报（英文版）

基　　金：financially supported by the National Natural Science Foundation of China(NSFC,Nos.21501133,22371067);the China Hunan Provincial Science&Technology Department(Nos.2020RC3020 and 2021JJ20021)。

摘　　要：Small-molecule drugs are widely used in daily life.There are still issues with the current industrial synthesis techniques for small-molecule drugs,such as the use of expensive metal catalysts,convoluted reaction processes,and non-recyclable catalysts.The benefits of photocatalytic organic synthesis over conventional techniques are mild conditions,environmental friendliness,and great selectivity.Porous framework materials can precisely modulate catalytic sites'electronic state and ligand structure to improve photocatalytic performance.In particular,MOFs,COFs and PCCs based photocatalysts have received extensive research interest due to their unique morphology,structural adjustability,high photocatalytic performance,unique recyclability,excellent chemical stability,easy synthesis and low cost.Therefore,a key area for future research is the development of porous framework materials as photocatalysts for the synthesis of small-molecule drugs or drug precursors.

关 键 词：Small-molecule drug Porous framework materials PHOTOCATALYSIS 

分 类 号：O644.1[理学—物理化学] TQ460.32[理学—化学]