创伤性颅脑损伤后垂体功能减退  

Hypopituitarism after traumatic brain injury

作　　者：潘立 谢理政 程宏伟[1] 茆翔 Pan Li;Xie Lizheng;Cheng Hongwei;Mao Xiang(Department of Neurosurgery,The First Affiliated Hospital of Anhui Medical University,Hefei 230022,China)

机构地区：[1]安徽医科大学第一附属医院神经外科,合肥230022

出　　处：《中华神经创伤外科电子杂志》2023年第5期308-312,共5页Chinese Journal Of Neurotraumatic Surgery：Electronic Edition

基　　金：国家自然科学基金(82202438);安徽高校自然科学重点项目(KJ2020A0172);安徽省留学回国人员创新创业扶持计划项目(2020LCX016);北京市博士后基金项目(2020-ZZ-008)。

摘　　要：创伤性颅脑损伤(TBI)是青年人致死致残的重要原因,改善TBI患者的预后一直是临床医生研究的重点。TBI可以引起垂体功能减退(PTHP)导致体内激素水平紊乱,进而带来一系列临床症状,严重影响患者预后。随着人们对TBI后PTHP认识的逐渐提高,针对PTHP的诊断及治疗的研究也在逐步深入。本文主要从PTHP的流行病学、临床表现、发病机制及诊断治疗等方面作一综述。Traumatic brain injury(TBI)is an important cause of death and disability in young people,and improving the prognosis of TBI patients has always been a focus of clinical research.TBI can cause posttraumatic hypopituitarism(PTHP),leading to hormone level disorder in the body,which can lead to a series of clinical symptoms and seriously affect the prognosis of patients.With the gradual improvement of people’s understanding of PTHP after TBI,studies on the diagnosis and treatment of PTHP are also gradually deepening.This article mainly reviews the epidemiology,clinical manifestations,pathogenesis,diagnosis and treatment of PTHP.

关 键 词：创伤性颅脑损伤 垂体功能减退 激素水平 预后 

分 类 号：R651.15[医药卫生—外科学]