三级淋巴结构在器官移植排斥反应中的现状与展望  

Current status and prospects of tertiary lymphatic structures in organ transplant rejection reactions

作　　者：杨麒臻 王英 陈乾 牛玉林 YANG Qizhen;WANG Ying;CHEN Qian;NIU Yulin(Department of Organ Transplantation,the Affiliated Hospital of Guizhou Medical University,Guiyang,Guizhou,550000;Department of Neurology,the Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine,Guiyang,Guizhou,550000)

机构地区：[1]贵州医科大学附属医院器官移植科,贵州贵阳550000 [2]贵州中医药大学第二附属医院神经内科,贵州贵阳550000

出　　处：《实用临床医药杂志》2024年第5期144-148,共5页Journal of Clinical Medicine in Practice

基　　金：2023年贵州省基础研究计划(自然学科类)项目[黔科合基础-ZK(2023)一般380]。

摘　　要：器官移植后,移植物的排斥反应是最常见的并发症之一,无论病因如何都会对移植物产生不良损害。三级淋巴结构(TLS)于病理情况下非淋巴组织内发生。针对调节移植物排斥反应的机制鉴定和表征,不仅能够促进人们对器官移植物的存活及预后的理解,而且还为治疗移植物排斥反应提供了思路。s:After organ transplantation,graft rejection is one of the most common complications,which will cause adverse injuries to grafts regardless of etiology.Tertiary lymphoid structures(TLS)occur in non-lymphoid tissues under pathological conditions.Identification and characterization of mechanisms regulating graft rejection can not only promote understanding of the survival and prognosis of organ grafts,but also provide ideas for treating graft rejection reaction.

关 键 词：三级淋巴结构 器官移植 移植物排斥反应 发病机制 

分 类 号：R458[医药卫生—治疗学] R617[医药卫生—临床医学] R496