针灸治疗偏头痛作用机制研究进展  

Research Progress in Action Mechanism of Acupuncture and Moxibustion in Treating Migraine

作　　者：李星[1,2,3] 沈燕 彭拥军[4] LI Xing;SHEN Yan;PENG Yongjun(Tianjin University of Traditional Chinese Medicine,Tianjin,China,301617;The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin,China,300183;National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion,Tianjin,China,300183;Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing,Jiangsu,China,210004)

机构地区：[1]天津中医药大学,天津301617 [2]天津中医药大学第一附属医院,天津300183 [3]国家中医针灸临床医学研究中心,天津300183 [4]南京中医药大学附属医院,江苏南京210004

出　　处：《河南中医》2024年第4期614-620,共7页Henan Traditional Chinese Medicine

基　　金：国家自然科学基金青年科学基金项目(81303020);天津市自然科学基金重点项目(18JCZDJC99200)。

摘　　要：针灸治疗偏头痛的机制主要包括调节脑部血流速度、影响神经递质释放、抑制炎性反应、调节中枢镇痛机制、抑制神经元激活、抑制胶质细胞活化、促进阿片类受体、调节脑-肠-菌轴等。目前,针灸治疗偏头痛临床研究逐渐丰富,但仍存在以下问题:治法相对单一,主要集中在针刺研究方向;没有区别证型,未发挥最大疗效;缺乏对机制之间联系及整体的研究等。今后,可加强对灸法治疗偏头痛机制的研究,促进临床治疗多样性,充分发挥针灸治疗偏头痛的作用;研究针灸治疗不同证型偏头痛机制的区别,充分考虑患者个体差异性,提高临床疗效;进一步挖掘不同机制之间的内在联系,促进针灸治疗偏头痛整体机制研究的发展。The mechanism of acupuncture and moxibustion in treating migraine mainly includes regulating cerebral blood flow velocity,affecting neurotransmitter release,inhibiting inflammatory response,regulating central analgesia mechanism,inhibiting neuronal activa-tion,inhibiting glial cell activation,promoting opioid receptors,and regulating brain-gut-bacterial axis.At present,the clinical re-search on acupuncture and moxibustion treatment of migraine is gradually enriched,but there are still the following problems:The treat-ment is relatively simple,mainly focusing on acupuncture;There is no differentiation in syndrome types and the maximum therapeutic effect has not been achieved;lack of research on the connections between mechanisms and the overall situation.In the future,it is neces-sary to strengthen the research on the mechanism of moxibustion treatment of migraine,promote the diversity of clinical treatment,and maximize the efficacy of acupuncture and moxibustion;to study whether the mechanism of acupuncture and moxibustion in treating mi-graine of different syndromes is dfferent,fully consider the individual dfferences of patients,and improve the clinical efficacy;to further explore the internal relationship between different mechanisms,and promote the development of the research on the overall mechanism of acupuncture and moxibustion treatment of migraine.

关 键 词：偏头痛 针灸疗法 神经递质 炎性反应 胶质细胞 阿片类受体 脑-肠-菌轴 

分 类 号：R246.6[医药卫生—针灸推拿学]