中医药治疗血液透析伴焦虑或抑郁障碍研究进展  

Research Progress in the Treatment of Hemodialysis with Anxiety or Depression Disorders with TCM

作　　者：唐好知 刘洋 李婉雯 渠雅君 郝娜[1,2] TANG Haozhi;LIU Yang;LI Wanwen;QU Yajun;HAO Na(First Teaching Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin,China,300381;National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion,Tianjin,China,300381)

机构地区：[1]天津中医药大学第一附属医院,天津300381 [2]国家中医针灸临床医学研究中心,天津300381

出　　处：《河南中医》2024年第4期642-648,共7页Henan Traditional Chinese Medicine

基　　金：国家自然科学基金青年基金项目(81904141);湖北陈孝平科技发展基金会2022年度免疫性疾病研究槐杞黄专项基金项目(CXPJJH122003-09);天津市科技计划项目(22KPHDRC00040)。

摘　　要：血液透析是终末期尿毒症患者常用的肾脏替代疗法之一,但长期血液透析可导致患者出现焦虑或抑郁等心理问题。中医药治疗血液透析伴焦虑或抑郁障碍的方法包括中医内治法、中医外治法、复合疗法等。其中,中医内治法包括经方疗法、时方疗法、自拟方疗法、中成药疗法等;中医外治法包括穴位疗法、中药足浴、五行音乐疗法、运动疗法等;复合疗法联合中药内服外治及常规西药和护理,疗效优于单一治疗。目前的研究仍存在一些不足,如缺乏规范的辨证分型、作用机制尚不明确、临床样本量有限、缺乏严谨的随机对照试验等。今后,应扩大样本量,严格实施随机对照试验,并探索具体的作用机制,以提供更多高质量的证据支持中医药治疗血液透析伴焦虑或抑郁障碍的临床效果。此外,中医外治法应成为血液透析伴焦虑、抑郁障碍的重点研究方向之一。Hemodialysis is one of the commonly used kidney replacement therapies for end-stage uremia patients,but long-term hemodi-alysis can lead to psychological problems such as anxiety or depression.TCM treatments include internal treatments,external treatments,compound therapies,etc.Among them,TCM internal treatments include classic formula therapy,updated formula therapy,self-made for-mula therapy,Chinese patent medicine therapy,etc.TCM external treatments include acupoint therapy,Chinese medicine foot bath,five-element music therapy,exercise therapy,etc.The effect of compound therapy combined with Chinese medicine for oral administration and external use and conventional Western medicine and nursing is better than that of any single therapy.There are still some shortcom-ings in the current research,such as lack of clear differentiation and classification of syndrome,unclear mechanism of action,limited clinical sample size,and lack of rigorous randomized controlled trials.In the future,the sample size should be expanded,randomized controlled trials should be strictly implemented,and specific mechanisms of action should be explored to provide more high-quality evi-dence to support the clinical effect of TCM in the treatment of hemodialysis with anxiety or depression disorders.In addition,TCM exter-nal treatment should become one of the key research directions of hemodialysis with anxiety and depression disorders.

关 键 词：血液透析 焦虑 抑郁障碍 中医内治法 中医外治法 复合疗法 

分 类 号：R277.7[医药卫生—中医学]