不同性别早发急性冠脉综合征患者危险因素及病变特点分析  

Analysis of risk factors and lesion characteristics in patients with premature acute coronary syndrome of different genders

作　　者：尹萍[1] 范例[1] 胡靖超[1] 卓杨[1] 曾华甦 许左隽[1] YIN Ping;FAN Li;HU Jing-chao;ZHUO Yang;ZENG Hua-su;XU Zuo-jun(Department of Cardiology,Ninth Affiliated People's Hospital of Medical College,Shanghai Jiaotong University,Shanghai,200011,China)

机构地区：[1]上海交通大学医学院附属第九人民医院心内科,上海200011

出　　处：《心血管康复医学杂志》2024年第2期136-139,共4页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：目的:探讨不同性别早发急性冠脉综合征(PACS)患者的危险因素及病变特点。方法:选择上海交通大学医学院附属第九人民医院心内科2016年1月至2019年1月收治的PACS患者338例,按性别分为男性组(195例)和女性组(143例),比较两组患者的基线资料、ACS分型、实验室检查指标、冠状动脉病变以及心脏结构变化情况。结果:与男性组比较,女性组年龄、糖尿病、脑梗死、不稳定型心绞痛比例、HDL-C、载脂蛋白A1、载脂蛋白A1/B水平显著升高,BMI、吸烟史、饮酒史、心肌梗死史、STEMI、NSTEMI比例,TG水平显著降低,P<0.05或<0.01;女性组单支病变比例(30.3%比40.6%)显著升高,左回旋支病变(56.9%比43.4%)、左室舒张末内径增大(6.2%比1.4%)和室间隔厚度增厚比例(16.9%比8.4%)显著降低,P均<0.05。结论:早发急性冠脉综合征患者中,男性吸烟率、TG水平显著升高,而女性患者脑梗死比例、HDL-C水平显著升高,左回旋支病变比例显著降低。两者之间存在显著差异。Objective:To investigate the risk factors and lesion characteristics in patients with premature acute coronary syndrome(PACS)of different genders.Methods:A total of 338 PACS patients admitted to the Department of Cardiology,Ninth Affiliated People's Hospital of Medical College of Shanghai Jiaotong University from January 2016 to January 2019 were selected.According to gender,they were divided into male group(n=195)and female group(n=143).Baseline data,ACS type,laboratory examination indexes,condition of coronary artery disease and cardiac structural changes were compared between two groups.Results:Compared with male group,there were significant rise in age,percentages of diabetes,cerebral infarction and unstable angina pectoris,levels of HDL-C,apolipoprotein(Apo)A1,Apo A1/B,and significant reductions in BMI,percentages of smoking,drinking,myocardial infarction history,STEMI and NSTEMI,and TG level in female group,P<0.05 or<0.01;significant rise in percentage of single vessel coronary disease(30.3%vs.40.6%),and significant reductions in percentages of left circumflex artery lesion(56.9%vs.43.4%),increased left ventricular end-diastolic diameter(6.2%vs.1.4%)and thickened interventricular septal thickness(16.9%vs.8.4%)in female group,P<0.05 all.Conclusion:In patients with premature acute coronary syndrome,men have significant higher smoking rate and TG level,while female patients have a significant higher proportion of cerebral infarction and HDL-C level,and significant lower proportion of left circumflex artery lesion.There are significant differences between the two genders.

关 键 词：急性冠状动脉综合征 性别 危险因素 

分 类 号：R542.209[医药卫生—心血管疾病]