Safety and efficacy of omalizumab for antihistamine-resistant chronic urticaria in children:a case series and literature review  

作　　者：Wei-Fang Zhu Chen Wang Jian-Jun Qiao Lan-Juan Li 

机构地区：[1]Department of Dermatology,First Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310003,China [2]State Key Laboratory for Diagnosis and Treatment of Infectious Diseases,National Clinical Research Center for Infectious Diseases,Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases,The First Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310003,China

出　　处：《World Journal of Pediatrics》2024年第3期294-298,共5页世界儿科杂志（英文版）

基　　金：supported by a grant from Zhejiang Provincial Natural Science Foundation of China(LGF21H190004).

摘　　要：Chronic urticaria(CU)is a common skin disease characterized by the occurrence of wheals,with or without angioedema,lasting more than 6 weeks.The prevalence of CU is about 0.7%[1],but higher in children,with an incidence of 1.38%[1].The occurrence of severe pruritus and unpredictable wheals may severely impact patients'quality of life,cause psychological problems,including sleep disorders and depression,and lead to economic burden due to limitation on daily life and work[2,3].

关 键 词：EDEMA PREVALENCE CHILDREN 

分 类 号：R725.1[医药卫生—儿科]