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作 者:汪涛[1] 陈东[1] 徐洲[1] 王钟颖[1] 王珮华[1] Wang Tao;Chen Dong;Xu Zhou;Wang Zhongying;Wang Peihua(Department of Otorhinolaryngology Head and Neck Surgery,Shanghai Ninth People′s Hospital,School of Medicine,Shanghai Jiao Tong University,Shanghai 200011,China)
机构地区:[1]上海交通大学医学院附属第九人民医院耳鼻咽喉头颈外科,上海200011
出 处:《中华耳鼻咽喉头颈外科杂志》2024年第3期212-218,共7页Chinese Journal of Otorhinolaryngology Head and Neck Surgery
基 金:上海交通大学医学院附属第九人民医院临床研究助推计划(临+计划)(JYLJ202009)。
摘 要:目的通过数值模拟研究正常鼻腔中鼻腔主观通畅感、鼻瓣区大小和气流动力学参数之间的相关关系,探讨鼻瓣区对鼻主观通畅感和鼻腔气流的影响作用。方法 2023年1—8月于上海交通大学医学院附属第九人民医院耳鼻咽喉头颈外科门诊选取52名健康受试者,其中男性31名,女性21名,平均年龄37.8岁。对受试者进行鼻主观通畅感视觉模拟量表(Visual Analog Scale,VAS)评分(双侧分别评分),运用数值模拟分析计算静息吸气状态下气流的动力学参数,通过统计学相关性矩阵分析这些主观和客观参数之间的相关程度。结果 VAS评分与单侧鼻瓣区截面积(r=-0.85,P<0.01)和单侧鼻内气流(r=-0.57,P<0.01)呈负相关,与单侧下鼻甲前端鼻阻力(nasal resistance,NR)呈正相关(r=0.61,P<0.01)。单侧鼻瓣区横截面积为(0.85±0.35)cm^(2)(xˉ±s,后同),与单侧鼻腔NR呈中等程度负相关(r=-0.50,P<0.01),与单侧鼻气流量呈正相关(r=0.61,P<0.01)。鼻瓣区NR占全部单侧鼻腔NR的(40.41±23.54)%,近一半的单侧NR[(46.74±21.38)%]和鼻腔加温效率[(49.96±10.02)%]存在于下鼻甲前端之前。结论鼻瓣区可影响鼻腔NR、单侧鼻内气流量和鼻腔气流温度变化,并与鼻腔主观通畅感存在关联。Objective To investigate the correlations between subjective nasal patency,nasal valve area size and aerodynamic parameters in normal nasal cavity by means of numerical simulation,and to explore the effect of nasal valve on nasal subjective sensation and nasal airflow regulation.Methods A total of 52 healthy participants(31 males and 21 females)with the average age of 37.8 years,were recruited from the outpatient Department of Otorhinolaryngology Head and Neck Surgery,the Ninth People′s Hospital Affiliated to the Medical College of Shanghai Jiao Tong University between January and August 2023.Visual Analog Scale(VAS)scores for unilateral nasal subjective sensation were obtained from all participants.Additionally,the aerodynamic characteristics of inspiratory airflow were simulated.A correlation matrix analysis was conducted to identify the correlation strength between these subjective and objective parameters.Results VAS scores showed negative correlations with unilateral nasal valve cross-sectional area(r=-0.85,P<0.01)and unilateral intranasal airflow(r=-0.57,P<0.01),and was a positive correlation with unilateral nasal resistance(NR)at the front-end of inferior turbinate(r=0.61,P<0.01).The average cross-sectional area of unilateral nasal valve was(0.85±0.35)cm2.The cross-sectional area of unilateral nasal valve was negatively correlated with unilateral NR(r=-0.50,P<0.01),and positively correlated with unilateral nasal airflow(r=0.61,P<0.01).The NR at the nasal valve area accounted for(40.41±23.54)%of the total unilateral NR.Nearly half of the unilateral NR[(46.74±21.38)%]and air warming[(49.96±10.02)%]occurring before the front end of inferior turbinate were achieved.Conclusions The nasal valve area plays a crucial role in influencing nasal NR,unilateral nasal airflow,and changes in nasal airflow temperature.Moreover,it is associated with subjective perception of nasal patency.
分 类 号:R765[医药卫生—耳鼻咽喉科]
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