三才配穴法埋线联合滋阴疏肝镇潜方对肝阳上亢型原发性高血压患者血管紧张素Ⅱ水平的影响  

Efficacy observation of catgut-embedding therapy by San Cai acupoint selection method combined with Zi Yin Shu Gan Zhen Qian prescription on the level of angiotensin in patients with essential hypertension of Ⅱ hyperactivity of liver Yang pattern

作　　者：李孔正 林秋意 吴光龙 张为 梁基源 黄基明 LI Kongzheng;LIN Qiuyi;WU Guanglong;ZHANG Wei;LIANG Jiyuan;HUANG Jiming(The Eighth Clinical Medical College of Guangzhou University of Chinese Medicine,Foshan 528000,China;People’s Hospital of Yangjiang,Guangdong,Yangjiang 529500,China)

机构地区：[1]广州中医药大学第八临床医学院,佛山528000 [2]广东省阳江市人民医院,阳江529500

出　　处：《上海针灸杂志》2024年第4期389-393,共5页Shanghai Journal of Acupuncture and Moxibustion

基　　金：广东省中医药局中医药科研项目(20212269)。

摘　　要：目的观察三才配穴法埋线联合滋阴疏肝镇潜方对肝阳上亢型原发性高血压患者血压、临床症状以及血清血管紧张素Ⅱ和肾素水平的影响。方法选取124例肝阳上亢型原发性高血压患者为研究对象,采用奇偶数分组法分为观察组(63例)和对照组(61例)。对照组予苯磺酸氨氯地平片联合滋阴疏肝镇潜方治疗,观察组在对照组口服药物治疗基础上联合三才配穴法埋线治疗。比较两组治疗前后中医证候积分、24 h平均血压和血压昼夜节律,观察两组治疗前后血清血管紧张素Ⅱ(angiotensinⅡ,AngⅡ)和肾素水平的变化。结果治疗后,两组24 h平均收缩压和舒张压以及中医证候积分均较治疗前降低(P<0.05),且观察组低于对照组(P<0.05)。治疗后,两组收缩压和舒张压昼夜节律明显改善(P<0.05),且观察组优于对照组(P<0.05)。治疗后,两组血清AngⅡ和肾素水平较治疗前降低(P<0.05),且观察组均低于对照组(P<0.05)。结论在口服苯磺酸氨氯地平片基础上,三才配穴法埋线联合滋阴疏肝镇潜方治疗肝阳上亢型原发性高血压可改善患者临床症状,降低血压,可能与抑制血清血管紧张素Ⅱ和肾素水平有关。Objective To observe the effect of catgut-embedding therapy by San Cai acupoint selection method combined with Zi Yin Shu Gan Zhen Qian prescription on blood pressure,clinical symptoms and serum levels of angiotensin and renin in patients with essential hypertension of hyperactivity of liver Yang Ⅱ pattern.Method One hundred and twenty-four patients with essential hypertension of hyperactivity of liver Yang pattern were selected as the research objects,and were divided into an observation group(63 cases)and a control group(61 cases)by odd and even grouping method.The control group was treated with Amlodipine besylate tablets combined with Zi Yin Shu Gan Zhen Qian prescription,and the observation group was treated with catgut-embedding therapy by San Cai acupoint selection method on the basis of oral medication in the control group.The TCM syndrome score,24 h average blood pressure and circadian rhythm of blood pressure were compared between the two groups before and after treatment.The changes of serum angiotensin Ⅱ(Ang)and renin levels were observed before and after treatment in the two groups.Ⅱ Result After treatment,the 24 h average systolic blood pressure,diastolic blood pressure and TCM syndrome scores of the two groups were lower than those before treatment(P<0.05),and those of the observation group was lower than those of the control group(P<0.05).After treatment,the circadian rhythms of systolic blood pressure and diastolic blood pressure in the two groups were significantly improved(P<0.05),and those in the observation group were better than those in the control group(P<0.05).After treatment,the serum levels of Ang and renin in the two groups were lower Ⅱ than those before treatment(P<0.05),and those in the observation group were lower than those in the control group(P<0.05).Conclusion On the basis of oral Amlodipine besylate tablets,catgut-embedding therapy by San Cai acupoint selection method combined with Zi Yin Shu Gan Zhen Qian prescription can improve the clinical symptoms and reduce blood

关 键 词：埋线 针药并用 配穴法 原发性高血压 肝阳上亢 

分 类 号：R246.1[医药卫生—针灸推拿学]