不同灸法治疗原发性痛经的随机对照试验  

A randomized controlled trial of different moxibustion for primary dysmenorrhea

作　　者：岳铭坤 周良荣[1] 薛晓[2] 李娟[1] 汪少华 黄慧源 袁菡钰 李凯 YUE Mingkun;ZHOU Liangrong;XUE Xiao;LI Juan;WANG Shaohua;HUANG Huiyuan;YUAN Hanyu;LI Kai(Hunan University of Traditional Chinese Medicine,Changsha 410208,China;The First Affiliated Hospital of University of South China,Hengyang 421001,Chin)

机构地区：[1]湖南中医药大学,长沙410208 [2]南华大学附属第一医院,衡阳421001

出　　处：《上海针灸杂志》2024年第4期439-444,共6页Shanghai Journal of Acupuncture and Moxibustion

基　　金：湖南省自然科学基金青年项目(2023JJ40598);湖南中医药大学研究生创新课题(2022CX21);湖南省卫生经济与信息学会项目(2022B10);南华大学临床医学研究“4310”重点项目(20214310ONHYCG04)。

摘　　要：目的观察采用智能中医灸疗床进行灸法治疗寒凝血瘀型原发性痛经的临床疗效。方法将60例寒凝血瘀型原发性痛经患者随机分为灸疗床组和局部灸组,每组30例。观察两组治疗前后血清环氧化酶-2(cyclooxygenase-2,COX-2)水平、疼痛视觉模拟量表(visual analog scale,VAS)评分、中医证候积分、焦虑自测量表(self anxious scale,SAS)评分及抑郁自测量表(self depression scale,SDS)评分的变化。比较两组临床疗效。结果灸疗床组总有效率为96.7%,局部灸组总有效率为86.7%,组间差异具有统计学意义(P<0.05)。治疗后及3次随访时,两组VAS评分均较治疗前降低(P<0.05);第2次和第3次随访时,灸疗床组VAS评分均低于局部灸组(P<0.05);第3次随访时,局部灸组VAS评分高于同组治疗后。治疗后及3次随访时,两组中医证候积分均低于同组治疗前(P<0.05)。治疗后,两组血清COX-2水平均低于同组治疗前(P<0.05)。治疗后及3次随访时,两组SAS和SDS评分均低于同组治疗前(P<0.05);治疗后及第2次随访时,灸疗床组SAS评分低于局部灸组(P<0.05);第2次和第3次随访时,灸疗床组SDS评分低于局部灸组(P<0.05)。结论采用智能中医灸疗床进行灸法治疗寒凝血瘀型原发性痛经的临床疗效优于局部灸,可缓解疼痛,改善临床症状。Objective To observe the clinical efficacy of intelligent moxibustion treatment bed for primary dysmenorrhea of cold induced blood stasis pattern.Method Sixty patients with primary dysmenorrhea of cold induced blood stasis pattern were randomized to a moxibustion treatment bed group and a topical moxibustion group,with 30 cases in each group.Serum cyclooxygenase-2(COX-2)levels were measured and the pain visual analog scale(VAS)score,the TCM syndrome score,the self anxious scale(SAS)score and the self depression scale(SDS)score were recorded in the two groups before and after treatment.The clinical therapeutic effects were compared between the two groups.Result The total efficacy rate was 96.7% in the moxibustion treatment bed group and 86.7% in the topical moxibustion group with a statistically significant between-group difference(P<0.05).At the end of treatment and three follow-ups,the VAS scores decreased in the two groups compared with those before treatment(P<0.05).At the second and third follow-ups,the VAS scores were lower in the moxibustion treatment bed group than those in the topical moxibustion group(P<0.05).At the third follow-up,the VAS score increased in the topical moxibustion group compared with that at the end of treatment(P<0.05).At the end of treatment and three follow-ups,the TCM syndrome scores decreased in the two groups compared with those before treatment(P<0.05).After treatment,serum COX-2 levels decreased in the two groups compared with those before(P<0.05).At the end of treatment and three follow-ups,the SAS and SDS scores decreased in the two groups compared with those before treatment(P<0.05).At the end of treatment and the second follow-up,the SAS scores were lower in the moxibustion treatment bed group than those in the topical moxibustion group(P<0.05).At the second and third follow-ups,the SDS scores were lower in the moxibustion treatment bed group than those in the topical moxibustion group(P<0.05).Conclusion Intelligent moxibustion treatment bed is clinically more effective than

关 键 词：灸法 针灸器械 电灸 温灸器灸 痛经 寒凝血瘀型 

分 类 号：R246.3[医药卫生—针灸推拿学]