治疗性单采红细胞罕见不良反应2例  

Rare adverse reactions to therapeutic erythrocytes apheresis:a report of two cases

作　　者：吴玲 甘新宇 谭强 张利 彭涛 WU Ling;GAN Xinyu;TAN Qiang;ZHANG Li;PENG Tao(Department of Blood Transfusion,the General Hospital of Western Theater Command,Chengdu 610083,China)

机构地区：[1]西部战区总医院输血医学科,四川成都610083

出　　处：《中国输血杂志》2024年第4期462-465,共4页Chinese Journal of Blood Transfusion

摘　　要：目的 通过对2例治疗性单采红细胞患者发生的罕见不良反应的分析,探讨治疗性单采红细胞更多地排除标准及不良反应的可能性。方法 2例有治疗性单采红细胞适应证的患者,使用单采技术从患者体内采集出红细胞保存备用或弃去。结果 其中1例采集后出现持续性房颤及痛风发作;1例采集中出现持续性低血压及采后血红蛋白的持续降低。结论 严格掌握治疗性单采红细胞的排除标准,加强房颤及痛风患者采集全过程监测,对减少不良反应的发生至关重要。Objective To investigate additional exclusion criteria for therapeutic apheresis erythrocytes and the possibility of adverse reactions by analyzing the occurrence of rare adverse reactions in two patients who underwent therapeutic erythrocytes apheresis.Methods Erythrocytes were harvested by apheresis from two patients with indications for therapeutic erythrocytes collection for preservation or discarding.Results One case experienced persistent atrial fibrillation and a gout attack after the collection,while another case experienced persistent hypotension during the collection and a subsequent reduction in haemoglobin levels after collection Conclusion To reduce the incidence of adverse reactions,it is essential to have strict exclusion criteria for therapeutic erythrocytes apheresis and to enhance the monitoring of whole collection process in patients with atrial fibrillation and gout.

关 键 词：治疗性单采红细胞 排除标准 不良反应 

分 类 号：R457.14[医药卫生—治疗学] R331.141[医药卫生—临床医学]