抗-HCV亲合力检测方法的研究进展  

Research progress on methods for anti-HCV avidity detection

作　　者：赫晓霞 郭文惠 曹荣凯 邢文革[2] HE Xiaoxia;GUO Wenhui;CAO Rongkai;XING Wenge(The Affiliated Hospital of Inner Mongolia Medical University,Clinical Laboratory Center,Hohhot 010110,Inner Mongolia Autonomous Region,China;National Center for AIDS/STD Control and Prevention,Chinese Center for Disease Control and Prevention.Beijing 102206,China)

机构地区：[1]内蒙古医科大学附属医院临床检验中心,呼和浩特010110 [2]中国疾病预防控制中心性病艾滋病预防控制中心参比实验室,北京102206

出　　处：《中国艾滋病性病》2024年第3期321-324,共4页Chinese Journal of Aids & STD

基　　金：内蒙古自治区人才科研项目。

摘　　要：HCV感染易造成国家较高的疾病负担。HCV感染后宿主产生的抗体亲合力随感染时间延长逐渐升高,亲合力测定可应用于HCV近期感染鉴别、发病率估算等。本文从抗-HCV IgG亲合力检测的方法学原理和建立、影响因素和临床应用等方面对抗-HCV IgG亲合力检测方法的研究现状进行综述,旨在为抗-HCV IgG方法学的标准化建立提供参考。Hepatitis C virus(HCV)infection contributes to a high national disease burden.The avidity of hostproduced antibodies to HCV infection steadily increases over time,and the avidity testing could be used to identify acute HCV infection,and to estimate HCV infection morbidity.This article reviews the current research status of the anti-HCV IgG avidity assay in the terms of methodological principles and establishment,influencing factors,and clinical applications,aiming to provide a reference for the standardization of anti-HCV IgG methodology.

关 键 词：丙型肝炎病毒 抗-丙型肝炎病毒 亲合力 检测 

分 类 号：R512.63[医药卫生—内科学]