A twist in the tale:global insights into archaeal box C/D RNA-guided 2′-O-methylation  

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作  者:Bin Li Jianhua Yang 

机构地区:[1]MOE Key Laboratory of Gene Function and Regulation,State Key Laboratory of Biocontrol,School of Life Sciences,Sun Yat-sen University,Guangzhou 510275,China [2]The Fifth Affiliated Hospital,Sun Yat-sen University,Zhuhai 519000,China

出  处:《Science China(Life Sciences)》2024年第4期849-850,共2页中国科学(生命科学英文版)

基  金:supported by the National Key Research and Development Program of China(2019YFA0802202,2022YFA1303300);the National Natural Science Foundation of China(32225011,31971228,31370791,91440110,32370588);Youth Science and Technology Innovation Talent of Guangdong TeZhi Plan(2019TQ05Y181)。

摘  要:The 2′-O-methylation of RNA stands as a dynamic and multifaceted modification,wielding significant influence over the regulation of RNA function,stability,and interactions within the cellular context(Sun et al.,2023).This particular modification targets the 2′-hydroxyl group of the ribose sugar embedded in the RNA backbone.

关 键 词:TWIST INSIGHT 

分 类 号:Q93[生物学—微生物学]

 

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