脑电双频指数监测下环泊酚复合布托啡诺用于无痛超声胃镜检查的临床效果  

Clinical Effect of Ciprofol Combined with Butorphanol for Painless Ultrasound Gastroscopy under Bispectral Index Monitoring

作　　者：薛小芬 叶秀清 XUE Xiaofen;YE Xiuqing(Department of Anesthesiology,Xiamen Haicang Hospital,Xiamen 361026,China;不详)

机构地区：[1]厦门市海沧医院麻醉科,福建厦门361026

出　　处：《中国医学创新》2024年第9期115-119,共5页Medical Innovation of China

摘　　要：目的:探讨脑电双频指数监测下环泊酚复合布托啡诺在无痛超声胃镜检查中的应用效果。方法:抽取2023年3—11月于厦门市海沧医院行无痛超声胃镜检查的患者78例为研究对象,采用随机数字表法分为对照组和试验组,各39例。两组均行环泊酚复合布托啡诺麻醉,对照组根据常规心电监护及麻醉医师经验指导用药,试验组根据脑电双频指数监测值指导用药。观察两组不同时点血流动力学变化情况,比较两组检查前后应激指标,并评估两组麻醉效果及安全性。结果:试验组插入胃镜即刻(T_(2))、退出胃镜即刻(T_(3))的收缩压(SBP)、心率(HR)、经皮动脉血氧饱和度(SpO_(2))均显著高于对照组,差异均有统计学意义(P<0.05);试验组检查后皮质醇(Cor)、醛固酮(ALD)、血管紧张素Ⅱ(AngⅡ)均显著低于对照组,差异均有统计学意义(P<0.05);试验组检查时间、清醒时间均显著短于对照组,差异均有统计学意义(P<0.05);试验组不良反应总发生率显著低于对照组,差异有统计学意义(P<0.05)。结论:针对行无痛超声胃镜检查的患者,在脑电双频指数监测下予以环泊酚复合布托啡诺麻醉,可减少检查期间血流动力学波动,减轻应激反应,缩短患者检查和麻醉清醒时间,且其能减少不良反应的发生。Objective:To investigate the application effect of Ciprofol combined with Butorphanol for painless ultrasound gastroscopy under bispectral index monitoring.Method:A total of 78 patients who underwent painless ultrasound gastroscopy in Xiamen Haicang Hospital from March to November 2023 were selected as the study objects,and they were divided into control group and experimental group according to random number table method,with 39 cases in each group.Both groups were given Ciprofol combined with Butorphanol anesthesia,the control group guided medication according to routine ECG monitoring and anesthesiologist's experience,and the experimental group guided medication according to bispectral index monitoring value.The hemodynamics changes of the two groups at different time points were observed,the stress indexes before and after examination were compared between the two groups,and the anesthetic effect and safety of the two groups were evaluated.Result:Systolic blood pressure(SBP),heart rate(HR)and percutaneous arterial oxygen saturation(SpO_(2))of experimental group immediately after gastroscope insertion(T_(2))and immediately after gastroscope withdrawal(T_(3))were significantly higher than those of control group,the differences were statistically significant(P<0.05).After examination,cortisol(Cor),aldosterone(ALD)and angiotensinⅡ(AngⅡ)in experimental group were significantly lower than those in control group,the differences were statistically significant(P<0.05).The examination time,waking time of experimental group were significantly shorter than those of control group,the differences were statistically significant(P<0.05).The total incidence of adverse reactions in experimental group was significantly lower than that in control group,the difference was statistically significant(P<0.05).Conclusion:For patients undergoing painless ultrasound gastroscopy,Ciprofol combined with Butorphanol anesthesia under bispectral index monitoring can reduce hemodynamics fluctuations during examination,alleviate stress resp

关 键 词：无痛超声胃镜检查 脑电双频指数 环泊酚 布托啡诺 

分 类 号：R614[医药卫生—麻醉学]