急性肾损伤生物标志物在急性肾损伤中的应用及中医药治疗进展  

Application of Acute Kidney Injury Biomarkers in Acute Kidney Injury and Progress of Chinese Medicine Treatment

作　　者：乔冬雪 高新 王孟孟 杨波[1] 杨洪涛[1] QIAO Dongxue;GAO Xin;WANG Mengmeng;YANG Bo;YANG Hongtao(First Teaching Hospital of Tianjin University of TCM,Tianjin 300000,China)

机构地区：[1]天津中医药大学第一附属医院,天津300000

出　　处：《西部中医药》2024年第4期101-105,共5页Western Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金(81774065,81303092)。

摘　　要：通过分析相关文献,探讨肾小球滤过功能标志物、近端小管损伤标志物、集合管损伤标志物、细胞周期阻滞蛋白等急性肾损伤生物标志物在急性肾损伤诊断中的应用情况,认为与传统实验室指标相比,急性肾损伤生物标志物各有其特点,可以代表肾脏不同部位的损伤,有助于急性肾损伤的早期预防、诊断和治疗。而中医药辨证论治该病具有一定经验,临床可根据需要进行辨证论治。By analyzing the relevant literature and discussing the application of acute kidney injury biomarkers such as glomerular filtration function marker,proximal tubular injury marker,collecting tubes injury marker and cell cycle blocking protein in the diagnosis of acute kidney injury,it is believed that,compared with the traditional laboratory indexes,each of these biomarkers has its own characteristics,and they can represent the injuries in different parts of the kidneys,which can help in the early prevention,diagnosis and treatment of acute kidney injury.Moreover,traditional Chinese medicine has certain experience in syndrome differentiation and treatment of this disease,and clinical syndrome differentiation and treatment can be carried out according to needs.

关 键 词：肾损伤 急性 生物标志物 胰岛素样生长因子结合蛋白7 金属蛋白酶2 研究进展 

分 类 号：R692[医药卫生—泌尿科学]