新癀片联合复方桐叶烧伤油治疗急性痛风性关节炎患者的疗效分析  

Effect of Xinhuang tablets combined with Fufang Tongye Shaoshang You for patients with acute gouty arthritis

作　　者：胡伟[1] 袁文霞 熊文佳 刘焕兵[1] Hu Wei;Yuan Wenxia;Xiong Wenjia;Liu Huanbing(Department of General Medicine,First Hospital,Medical College,Nanchang University,Nanchang 330200,China)

机构地区：[1]南昌大学第一附属医院全科医疗科,南昌330200

出　　处：《国际医药卫生导报》2024年第7期1152-1156,共5页International Medicine and Health Guidance News

基　　金：江西省中医药管理局科技计划(2021A015);中央引导地方科技发展资金(207257757023)。

摘　　要：目的观察新癀片联合复方桐叶烧伤油治疗急性痛风性关节炎的疗效。方法采用前瞻性干预性研究。选取2022年1月至12月在南昌大学第一附属医院接受治疗的96例急性痛风性关节炎患者作为研究对象,采用随机数字表法将其分为3组,每组32例。A组男28例、女4例,年龄(53.37±16.53)岁,急性病程(2.56±0.92)d,在常规治疗基础上加用新癀片外敷;B组男30例、女2例,年龄(54.18±17.42)岁,急性病程(2.53±0.89)d,在常规治疗基础上加用复方桐叶烧伤油;C组男29例、女3例,年龄(53.61±17.21)岁,急性病程(2.61±0.93)d,在常规治疗基础上采用新癀片+复方桐叶烧伤油外敷,干预周期均为1周。对比3组患者一般资料(年龄、性别、体质指数、饮酒、吸烟及急性病程)、治疗前及治疗后1、3、5、7 d视觉模拟评分法(VAS)评分、治疗前及治疗后1、3、5、7 d骨关节炎指数(WOMAC)、中医证候疗效。统计学方法采用t检验、χ^(2)检验。结果3组急性痛风性关节炎患者一般资料比较,差异均无统计学意义(均P>0.05)。治疗前及治疗后1 d,3组患者VAS评分比较,差异均无统计学意义(均P>0.05);治疗后3、5、7 d,3组患者VAS评分比较,差异均有统计学意义(均P<0.05);C组治疗后3、5、7 d的VAS评分[(4.84±1.30)分、(2.97±1.31)分、(1.81±1.15)分]均低于A组[(5.63±1.26)分、(4.34±1.33)分、(2.97±1.28)分]、B组[(6.38±1.21)分、(5.38±1.21)分、(5.38±1.21)分],差异均有统计学意义(均P<0.05)。治疗前及治疗后1 d,3组患者WOMAC评分比较,差异均无统计学意义(均P>0.05);治疗后3、5、7 d,3组患者WOMAC评分比较,差异均有统计学意义(均P<0.05);C组治疗后3、5、7 d的WOMAC评分[(113.50±28.78)分、(82.66±31.82)分、(50.19±34.90)分]均低于A组[(128.09±25.59)分、(110.31±28.29)分、(87.84±33.19)分]、B组[(154.19±20.59)分、(148.19±20.59)分、(137.28±20.62)分],差异均有统计学意义(均P<0.05)。C组总有效率为96.9%(27/32),�Objective To observe the curative effect of Xinhuang tablets combined with Fufang Tongye Shaoshang You for patients with acute gouty arthritis.Methods A total of 96 patients with acute gouty arthritis treated at First Hospital,Medical College,Nanchang University from January 2022 to December 2022 were selected,and divided into group A,group B,and group C by the random number table method,with 32 cases in each group.There were 28 males and 4 females in group A;they were(53.37±16.53)years old;their acute disease course was(2.56±0.92)d.There were 30 males and 2 females in group B;they were(54.18±17.42)years old;their acute disease course was(2.53±0.89)d.There were 29 males and 3 females in group C;they were(53.61±17.21)years old;their acute disease course was(2.61±0.93)d.The three groups were treated with conventional drugs;in addition,group A were treated with Xinhuang tablets,group B with Fufang Tongye Shaoshang You,and group C with Xinhuang tablets and Fufang Tongye Shaoshang You.All the three groups were observed 3 weeks.The general data(age,gender,body mass index,drinking,smoking,and acute disease course),scores of Visual Analogue Scale(VAS)and osteoarthritis index(WOMAC)before and 1,3,5,and 7 d after the treatment,and traditional Chinese medicine syndrome efficacies were compared between the 3 groups.t and χ^(2) tests were applied.Results There were no statistical differences in the general data between the three groups(all P>0.05).There were no statistical differences in the scores of VAS before and 1 d after the treatment between the three groups(both P>0.05).There were statistical differences in the scores of VAS 3,5,and 7 d after the treatment between the three groups(all P<0.05).The scores of VAS 3,5,and 7 d after the treatment in the group C[(4.84±1.30),(2.97±1.31),and(1.81±1.15)]were lower than those in group A[(5.63±1.26),(4.34±1.33),and(2.97±1.28)]and group B[(6.38±1.21),(5.38±1.21),and(5.38±1.21)],with statistical differences(all P<0.05).There were no statistical differences in the sc

关 键 词：痛风性关节炎 新癀片 复方桐叶烧伤油 肿胀 疼痛 

分 类 号：R259[医药卫生—中西医结合]