盐酸丙卡特罗颗粒治疗儿童喘息性疾病的效果观察  

Effect observation of procaterol hydrochloride granules in the treatment of children with asthmatic diseases

作　　者：谢磊 刘川玉[3] 陈山林 石桂俏 秦坤清 唐建红 XIE Lei;LIU Chuanyu;CHEN Shanlin;SHI Guiqiao;QIN Kunqing;TANG Jianhong(The Second Affiliated Hospital of Guilin Medical College,Guilin 541199,China;College of Pharmacy,Guilin Medical University,Guilin 541199,China;Affiliated Hospital of Guilin Medical University,Guilin 541001,China)

机构地区：[1]桂林医学院第二附属医院,桂林541199 [2]桂林医学院药学院,桂林541199 [3]桂林医学院附属医院,桂林541001

出　　处：《华夏医学》2024年第1期106-110,共5页Acta Medicinae Sinica

基　　金：2020年度广西医疗卫生适宜技术开发与推广应用项目(S2020106);2021年自治区级大学生创新创业训练计划项目(202110601012)。

摘　　要：目的观察盐酸丙卡特罗颗粒治疗儿童喘息性疾病的临床效果。方法90例喘息性疾病患儿依据不同的给药方案分为3组,每组30例。对照组采用常规药物治疗,丙卡特罗组为常规药物加盐酸丙卡特罗颗粒治疗,氨溴特罗组为常规药物加氨溴特罗口服液治疗。观察各组临床症状好转时间、不良反应发生率、复发住院和门诊就诊次数。结果丙卡特罗组的咳嗽好转时间、喘息好转时间、肺部哮鸣音好转时间均短于氨溴特罗组和对照组,差异具有统计学意义(P<0.05);3组不良反应总发生率比较,差异无统计学意义(P>0.05);丙卡特罗组1年内因喘息性疾病3次及以上门诊就诊发生率低于氨溴特罗组和对照组(P<0.05)。结论盐酸丙卡特罗颗粒治疗儿童喘息性疾病的临疗效果较好,安全性高,能减少疾病复发率。Objective To observe the clinical effect of procatterol hydrochloride granules in the treatment of children with asthmatic diseases.Methods 90 children with asthmatic diseases were included and divided into 3 groups according to different medication regimen,with 30 cases in each group.The control group were received conventional drugs,while the procatterol group were received conventional drugs plus procatterol hydrochloride granules,and the ambroterol group were received conventional drugs plus ambroterol oral liquid.The time of clinical symptoms improvement,the incidence of adverse reactions,and the number of recurrent hospitalization and outpatient visits were observed in each group.Results The improvement time of cough,dyspnea,wheezing and pulmonary wheezing in procatrol group was shorter than that in the ambroterol group and control group,and the difference was statistically significant(P<0.05).There was no significant difference in the total incidence of adverse reactions among the three groups(P>0.05).The incidence of 3 or more outpatient visits due to asthmatic diseases in the procaterol group was lower than that in the ambroterol group and control group within 1 year(P<0.05).Conclusion Procatterol hydrochloride is more clinically effective in the treatment of children with asthmatic diseases,which can reduce the recurrence rate of the disease.

关 键 词：盐酸丙卡特罗颗粒 氨溴特罗口服液 儿童喘息性疾病 

分 类 号：R562.25[医药卫生—呼吸系统]