两种不同术式治疗高危良性前列腺增生临床疗效的对比研究  

A comparative study on the clinical curative effect of two different surgical methods in treatment of high-risk benign prostatic hyperplasia

作　　者：许倩 邓慕夏 XU Qian;DENG Muxia(Department of Urology,Mengcheng County Second People′s Hospital,Mengcheng 233500,Anhui,China)

机构地区：[1]蒙城县第二人民医院泌尿外科,安徽蒙城233500

出　　处：《中国性科学》2024年第4期29-33,共5页Chinese Journal of Human Sexuality

基　　金：2021年度安徽省卫生健康委科研项目(AHWJ2021a043)。

摘　　要：目的对比研究经尿道双极等离子前列腺剜除术(TPKEP)和经尿道双极等离子前列腺电切术(TPKRP)对高危良性前列腺增生(BPH)的临床疗效。方法选取2020年10月至2023年6月蒙城县第二人民医院收治的100例高危BPH患者作为研究对象,根据治疗方法将其分为TPKEP组(n=57)和TPKRP组(n=43),TPKEP组给予TPKEP治疗,TPKRP组给予TPKRP治疗。比较两组术后并发症发生情况,术中手术指标(手术时间、术中出血量、腺体切割量),术前、术后6 h创伤应激因子[促肾上腺皮质激素(ACTH)、醛固酮(ALD)、皮质醇(Cor)]水平,术前及术后1个月、3个月国际前列腺症状评分(IPSS)和性生活质量情况[国际勃起功能指数问卷表-5(IIEF-5)、性生活质量调查量表-生活质量维度(SLQQ-QOL)评分]。结果两组术后并发症发生率比较,差异无统计学意义(P>0.05)。与TPKRP组比较,TPKEP组手术时间更短,术中出血量更少,腺体切割量更多;术后,TPKEP组患者ACTH、ALD和Cor水平更低;术后1个月、3个月,TPKEP组患者IIEF-5和SLQQ-QOL评分更高,IPSS更低(P<0.05)。结论TPKEP比TPKRP治疗更有利于高危BPH患者的病情恢复。Objective To compare the clinical curative effect of transurethral plasma kinetic enucleation of the prostate(TPKEP)and transurethral plasma kinetic resection of the prostate(TPKRP)in high-risk benign prostatic hyperplasia(BPH).Methods A total of 100 patients with high-risk BPH admitted to Mengcheng County Second People′s Hospital were enrolled as the research objects from October 2020 and June 2023.According to different treatment methods,they were divided into TPKEP group(n=57)and TPKRP group(n=43).TPKEP group was given TPKEP treatment and TPKRP group was given TPKRP treatment.The occurrence of postoperative complications,intraoperative surgical indicators(operation time,intraoperative blood loss,glandular incision volume),levels of traumatic stress factors[adrenocorticotropic hormone(ACTH),aldosterone(ALD),cortisol(Cor)]before and at 6 h after surgery,international prostate symptom score(IPSS)and sexual life quality[international index of erectile function-5(IIEF-5),sexual life quality questionnaire-quality of life dimension(SLQQ-QOL)]before surgery,at 1 month and 3 months after surgery were compared between the two groups.Results There was no significant difference in the incidence of postoperative complications between the two group(P>0.05).Compared with TPKRP group,operation time was shorter,intraoperative blood loss was less,and glandular incision volume was higher in TPKEP group.After surgery,levels of ACTH,ALD and Cor in TPKEP group were lower.At 1 month and 3 months after surgery,scores of IIEF-5 and SLQQ-QOL in TPKEP group were higher,while IPSS was lower(P<0.05).Conclusions Compared with TPKRP,TPKEP is more beneficial to the recovery of patients with high-risk BPH.

关 键 词：良性前列腺增生 经尿道双极等离子前列腺剜除术 经尿道双极等离子前列腺电切术 创伤应激 性功能 

分 类 号：R697[医药卫生—泌尿科学]