骨质疏松症“亏瘀致痿”的理论构建及临床应用  

Theory Construction and Clinical Application of"Flaccidity Caused by Deficiency and Congestion"in Osteoporosis

作　　者：姚新苗[1,2] YAO Xinmiao(The Third Affiliated Hospital of Zhejiang Chinese Medical University,Hangzhou,Zhejiang 310005,China;Zhejiang Rehabilitation Medical Center,Hangzhou,Zhejiang 310052,China)

机构地区：[1]浙江中医药大学附属第三医院,浙江杭州310005 [2]浙江康复医疗中心,浙江杭州310052

出　　处：《康复学报》2024年第2期97-102,109,共7页Rehabilitation Medicine

基　　金：国家自然科学基金项目(82074183)。

摘　　要：骨质疏松症(OP)是一种以增龄性骨量降低,骨微结构破坏,骨脆性增加且易骨折的代谢性骨病。该病好发于绝经后女性和中老年男性,起病隐匿,多数患者在骨折后才被确诊,造成了大量的医疗资源消耗。浙江中医药大学附属第三医院姚新苗教授研究团队基于“肾主骨”“肾气虚损”等基础理论,创新性提出了OP“亏瘀致痿”的致病理论,认为OP的病机是亏虚瘀互结、夹杂致痿。在该理论指导下,认为应采用“补肾健脾活血法”对OP患者进行辨证论治。补肾健脾活血法主要包括虚瘀同治;补肾为本、健脾为要;筋骨并重3个方面。该研究团队开展了一系列临床与基础研究,从不同角度阐释“亏瘀致痿”理论指导下OP康复策略的科学内涵。Osteoporosis(OP)is a metabolic bone disease characterized by an age-related loss of bone mass,destruction of bone microstructure,increased bone fragility and susceptibility to fracture.It is prevalent in postmenopausal women and middle-aged and elderly men and has an insidious onset.Most patients are diagnosed only after fracture,resulting in a significant consumption of medical resources.Based on the basic theories such as"kidney governing bone"and"kidney Qi deficiency",YAO Xinmiao's team in the Third Affiliated Hospital of Zhejiang Chinese Medical University innovatively puts forward the pathogenic theory of"flaccidity caused by deficiency and congestion"in OP,which holds that the pathogenesis of OP is the coexistence of deficiency and blood stasis,mixed with impotence.Under the guidance of this theory,it is believed that the"tonifying kidney,invigorating spleen and activating blood circulation"method should be used to treat patients with OP based on syndrome differentiation.This method consists of three main aspects,including the simultaneous treatment of deficiency and blood stasis;tonifying kidney and invigorating spleen;strengthening both tendons and bones.The research team conducted a series of clinical and basic studies to explain the scientific connotation of the OP rehabilitation strategy under the guidance of the theory of"flaccidity caused by deficiency and congestion"from different perspectives.

关 键 词：骨质疏松症 亏瘀致痿 补肾健脾活血法 中西医结合康复 

分 类 号：R580[医药卫生—内分泌]