妊娠早期先兆流产高龄孕妇保胎治疗后妊娠失败的影响因素  

Influencing factors of pregnancy failure after tocolytic therapy in elderly pregnant women with threatened abortion in early pregnancy

作　　者：罗颖怡 LUO Yingyi(Department of Obstetrics and Gynecology of Zhaoqing Central People’s Hospital,Sihui People’s Hospital,Zhaoqing 526200 Guangdong,China)

机构地区：[1]肇庆市中心人民医院四会市人民医院妇产科,广东肇庆526200

出　　处：《中国民康医学》2024年第7期5-7,12,共4页Medical Journal of Chinese People’s Health

摘　　要：目的:分析妊娠早期先兆流产高龄孕妇保胎治疗后妊娠失败的影响因素。方法:选取2021年1月至2023年1月该院收治的230例妊娠早期先兆流产高龄孕妇进行横断面研究,均进行保胎治疗,并判定妊娠结局,根据妊娠结局将其分为继续妊娠组和妊娠失败组。采用Logistic回归分析妊娠早期先兆流产高龄孕妇保胎治疗后妊娠失败的影响因素。结果:230例妊娠早期先兆流产高龄孕妇保胎治疗后妊娠失败45例,发生率为19.57%(45/230);两组年龄、孕周、孕次、孕前体质量指数、人工流产史、早产史、孕期吸烟史、孕期饮酒史、合并阴道炎比较,差异均无统计学意义(P>0.05);妊娠失败组黄体功能不全、有自然流产史、有宫内大血肿、β-人绒毛膜促性腺激素(β-hCG)<9000 mU/mL占比均高于继续妊娠组,差异有统计学意义(P<0.05)。Logistic回归分析结果显示,黄体功能不全、有自然流产史、有宫内大血肿、β-hCG<9000 mU/mL均为妊娠早期先兆流产高龄孕妇保胎治疗后妊娠失败的危险因素(OR>1,P<0.05)。结论:黄体功能不全、有自然流产史、有宫内大血肿、β-hCG<9000 mU/mL均为妊娠早期先兆流产高龄孕妇保胎治疗后妊娠失败的危险因素。Objective:To analyze influencing factors of pregnancy failure after tocolytic therapy in elderly pregnant women with threatened abortion in early pregnancy.Methods:A cross-sectional study was conducted on 230 elderly pregnant women with threatened abortion in early pregnancy admitted to this hospital from January 2021 to January 2023.All patients were treated with tocolytic therapy,and the pregnancy outcome was determined.According to the pregnancy outcome,they were divided into continued pregnancy group and pregnancy failure group.Logistic regression was used to analyze the influencing factors of pregnancy failure after tocolytic therapy in the elderly pregnant women with threatened abortion in early pregnancy.Results:There were 45 cases of pregnancy failure after tocolytic therapy in the 230 elderly pregnant women with threatened abortion in early pregnancy,with an incidence of 19.57%(45/230).There were no significant differences in age,gestational age,gravidity,pre-pregnancy body mass index,history of induced abortion,history of premature delivery,history of smoking during pregnancy,history of drinking during pregnancy,and combined vaginitis between the two groups(P>0.05).The proportions of the cases with luteal insufficiency,history of spontaneous abortion,large intrauterine hematoma,andβ-human chorionic gonadotropin(β-hCG)<9000 mU/mL in the pregnancy failure group were higher than those in the continuous pregnancy group,and the differences were statistically significant(P<0.05).Logistic regression analysis showed that luteal insufficiency,history of spontaneous abortion,large intrauterine hematoma,andβ-hCG<9000 mU/mL were risk factors for pregnancy failure after tocolytic therapy in the elderly pregnant women with threatened abortion in early pregnancy(OR>1,P<0.05).Conclusions:Luteal insufficiency,history of spontaneous abortion,large intrauterine hematoma,andβ-hCG<9000 mU/mL are the risk factors for pregnancy failure after tocolytic therapy in the elderly pregnant women with threatened abortion in early

关 键 词：妊娠早期 先兆流产 高龄 孕妇 保胎治疗 妊娠失败 影响因素 

分 类 号：R714.21[医药卫生—妇产科学]