超声造影联合超声弹性成像对临床触诊阴性乳腺结节良恶性的鉴别诊断效能  

differential diagnosis efficiency of contrast-enhanced ultrasound combined with ultrasound elastography in distinguishing benign and malignant breast nodules with clinical palpation negative

作　　者：王颖 WANG Ying(Department of Ultrasound of Xinxiang Central Hospital,the Fourth Clinical College of Xinxiang Medical College,Xinxiang 453000 Henan,China)

机构地区：[1]新乡市中心医院新乡医学院第四临床学院超声科,河南新乡453000

出　　处：《中国民康医学》2024年第7期145-148,共4页Medical Journal of Chinese People’s Health

摘　　要：目的:分析超声造影联合超声弹性成像对临床触诊阴性乳腺结节良恶性的鉴别诊断效能。方法:回顾性分析2020年6月至2022年6月在该院就诊的120例触诊阴性乳腺结节患者的临床资料,比较良恶性结节的超声造影参数[峰值强度(PI)、上升支斜率(WIS)、曲线下面积(AUC)、达峰时间(TTP)]、超声弹性成像参数[蓝色区域面积百分比(AREA%)、感兴趣区应变均值(MEAN)及标准差(SD)],并以病理结果为金标准,比较超声造影、超声弹性成像单独及联合检查对临床触诊阴性乳腺结节良恶性的鉴别诊断价值。结果:病理检查结果显示,120例触诊阴性乳腺结节患者中恶性结节74例(61.67%),良性结节46例(38.33%);恶性结节PI、WIS、AUC、AREA%、MEAN、SD值均大于良性结节,TTP值小于良性结节,差异有统计学意义(P<0.05);超声造影、超声弹性成像联合检查鉴别诊断临床触诊阴性乳腺恶性结节的灵敏度、准确度均高于二者单项诊断,差异有统计学意义(P<0.05);超声造影、超声弹性成像单独及联合检查鉴别诊断临床触诊阴性乳腺恶性结节的特异度比较,差异无统计学意义(P>0.05)。结论:超声造影、超声弹性成像对临床触诊阴性乳腺结节均有一定诊断价值,联合诊断的灵敏度、准确度均高于超声造影、超声弹性成像单项诊断。Objective:To explore differential diagnostic efficiency of contrast-enhanced ultrasound combined with ultrasound elastography in distinguishing benign and malignant breast nodules with clinical palpation negative.Methods:The clinical data of 120 patients with clinical palpation negative breast nodules who were treated in the hospital from June 2020 to June 2022 were retrospectively analyzed.The contrast-enhanced ultrasound parameters[peak intensity(PI),wash in slope(WIS),area under the curve(AUC),time to peak(TTP)]levels,the ultrasound elastography parameters[area percentage of blue area(AREA%),mean strain of interest(MEAN)and standard deviation(SD)]of benign and malignant nodules were compared.Using the pathological results as the gold standard,the efficiencies of contrast-enhanced ultrasound,ultrasound elastography single and combination examinations for the differential diagnosis of benign and malignant breast nodules with clinical palpation negative.Results:The pathological examination showed that there were 74 cases(61.67%)of malignant nodules and 46 cases(38.33%)of benign nodules in the 120 patients with palpation negative breast nodules.The levels of PI,WIS,AUC,AREA%,MEAN and SD of the malignant nodules were higher than those of the benign nodules,the TTP value was lower than that of the benign nodules,and the differences were statistically significant(P<0.05).The sensitivity and the accuracy of combined examination of contrast-enhanced ultrasound and ultrasound elastography in diagnosing clinical palpable negative breast malignant nodules were higher than those of single diagnosis,and the differences were statistically significant(P<0.05).There was no significant difference in the specificity of single and combined examination of contrast-enhanced ultrasound and ultrasound elastography in diagnosing clinical palpable negative breast malignant nodules(P>0.05).Conclusions:Contrast-enhanced ultrasound and ultrasonic elastography have certain diagnostic value for clinical palpation negative breast nodules.Fur

关 键 词：超声造影 超声弹性成像 乳腺癌 乳腺结节 诊断效能 

分 类 号：R445.1[医药卫生—影像医学与核医学]