广西壮族自治区壮族人群人类免疫缺陷病毒感染者及艾滋病患者心电图特征分析  

ECG characteristics of patients with human immunodeficiency virus infection and AIDS among Zhuang ethnic group in Guangxi Zhuang Autonomous Region

作　　者：庞磊 吴文英 黄妹青[2] 邵宏华 PANG Lei;WU Wenying;HUANG Meiqing;SHAO Honghua(Department of Electrocardiogram Diagnosis and Treatment,Nanning Fourth People’s Hospital(Guangxi AIDS Clinical Treatment Center),Nanning Guangxi 530023,China;AIDS Ward No.1,Nanning Fourth People’s Hospital(Guangxi AIDS Clinical Treatment Center),Nanning Guangxi 530023,China;Department of Cardiology,Nanning Fourth People’s Hospital(Guangxi AIDS Clinical Treatment Center),Nanning Guangxi 530023,China)

机构地区：[1]南宁市第四人民医院[广西艾滋病临床治疗中心(南宁)]心电诊疗科,广西南宁530023 [2]南宁市第四人民医院[广西艾滋病临床治疗中心(南宁)]艾滋病一病区,广西南宁530023 [3]南宁市第四人民医院[广西艾滋病临床治疗中心(南宁)]心内科,广西南宁530023

出　　处：《实用心电学杂志》2024年第2期133-136,共4页Journal of Practical Electrocardiology

基　　金：广西壮族自治区卫生健康委员会自筹经费科研课题项目(Z20210101)。

摘　　要：目的对广西壮族自治区壮族人群人类免疫缺陷病毒(human immunodeficiency virus,HIV)感染者及获得性免疫缺陷综合征(acquired immunodeficiency syndrome,AIDS)患者的心电图特征进行分析,为这类人群的诊断及治疗提供临床依据。方法纳入在广西壮族自治区内居住且在本院住院治疗的壮族人群中HIV感染者及AIDS患者各200例,分别作为感染组及患者组,并选取同期健康体检人群200例作为对照组。对三组研究对象进行常规12导联心电图检测,比较三组主动性心律失常、被动性心律失常、ST-T改变、QT间期/QTc延长及其他心电图异常改变的情况。结果感染组和患者组的主动性心律失常、被动性心律失常、QT间期/QTc延长发生率均明显高于对照组,且患者组这三类心电图异常改变的发生率亦显著高于感染组(P均<0.05)。结论广西壮族自治区壮族人群HIV感染者及AIDS患者心电图异常改变较为普遍,多是心律失常、ST-T改变和QT间期/QTc延长,需要临床医师密切关注这部分人群中HIV感染者及AIDS患者的心电图异常改变,以防不良心脏事件发生。Objective To analyze the ECG characteristics of patients with human immunodeficiency virus(HIV)infection and acquired immunodeficiency syndrome(AIDS)among Zhuang ethnic group in Guangxi Zhuang Autonomous Region so as to provide clinical basis for the diagnosis and treatment of this kind of population.Methods We selected 200 cases infected with HIV and 200 AIDS patients from inhabitants of Guangxi Zhuang Autonomous Region who had been hospitalized in our hospital,separately as infection group and patient group.In addition,200 healthy physical examinees during the same time period were selected as control group.Routine 12-lead ECG detection was performed on the three groups of research subjects.We compared active arrhythmia,passive arrhythmia,ST-T changes,QT interval/QTc prolongation and other abnormal ECG changes.Results In the infection group and the patient group,the incidences of active arrhythmias,passive arrhythmias,QT interval/QTc prolongation were all significantly higher than those in the control group.The incidences of the above three abnormal ECG changes in the patient group were also significantly higher than those in the infection group(all P<0.05).Conclusion Abnormal ECG changes are more common among patients with HIV infection and AIDS in Guangxi Zhuang population,mainly arrhythmias,ST-T changes and QT interval/QTc prolongation.Clinicians need to pay close attention to abnormal ECG changes of patients with HIV infection and AIDS patients among these population in order to prevent adverse cardiac events.

关 键 词：人类免疫缺陷病毒 获得性免疫缺陷综合征 心电图特征 心律失常 QT间期/QTc延长 壮族人群 

分 类 号：R512.91[医药卫生—内科学] R541.4[医药卫生—临床医学]