血清HCG、孕酮检测在诊断早期先兆流产中的临床意义  

The clinical significance of serum HCG and progesterone detection in the diagnosis of early threatened miscarriage

作　　者：周雪娟 Zhou Xuejuan(Department of Laboratory,Changshu Maternal and Child Health Hospital(Changshu Maternal and Child Health and Family Planning Service Center),Changshu 215500,China)

机构地区：[1]常熟市妇幼保健院(常熟市妇幼保健计划生育服务中心)检验科,江苏常熟215500

出　　处：《实用妇科内分泌电子杂志》2024年第5期104-106,共3页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的探讨血清人绒毛膜促性腺激素(HGG)及孕酮检测在早期先兆流产中的诊断价值。方法选取120例早期先兆流产孕妇为研究组,同期正常妊娠的10O例孕妇为对照组,两组均进行血清HGG与孕酮水平检测,比较两组的血清HGG与孕酮水平,以及其与早期先兆流产的相关性和单一检测与联合检测的诊断效能。结果研究组血清HGG、孕酮水平低于对照组(P<0.05);治疗后,继续妊娠组血清HGG、孕酮水平高于保胎失败组(P<0.05);血清HGG、孕酮水平均与早期先兆流产呈负相关(r=-0.427、-0.385,P<0.05);血清HGG与孕酮联合检测的AUC值、敏感度、特异度均高于单一检测(P<0.05)。结论在早期先兆流产中,采用血清HGG及孕酮联合检测能提高疾病的诊断准确率,且能进一步预测妊娠结局。Objective To explore the diagnostic value of serum human chorionic gonadotropin(HGG)and progesterone detection in early threatened miscarriage.Methods 120 pregnant women with early threatened miscarriage were selected as the study group,and 1oo pregnant women with normal pregnancy at the same time were selected as the control group.Both groups were tested for serum HGG and progesterone levels.The serum HGG and progesterone levels of the two groups were compared,as well as their correlation with early threatened miscarriage and the diagnostic efficacy of single and combined testing.Results The serum HGG and progesterone levels in the study group were lower than those in the control group(P<0.05);After treatment,the serum HGG and progesterone levels in the continued pregnancy group were higher than those in the failed pregnancy group(P<0.05);The levels of serum HGG and progesterone were negatively correlated with early threatened miscarriage(r=-0.427,-0.385,P<0.05);The AUC value,sensitivity,and specificity of the combined detection of serum HGG and progesterone were higher than those of a single detection(P<0.05).Conclusion In early threatened miscarriage,the combined detection of serum HGG and progesterone can improve the diagnostic accuracy of the disease and further predict pregnancy outcomes.

关 键 词：早期先兆流产 血清人绒毛膜促性腺激素 孕酮 诊断效能 

分 类 号：R714.21[医药卫生—妇产科学]