新冠病毒感染流行期间铜仁市疾控机构工作人员感染现况及疫苗保护效果评估  

Prevalence of SARS-CoV-2 infections and protective effect of COVID-19 vaccines among workers in disease control and prevention institutions in Tongren City during the SARS-CoV-2 infection

作　　者：胡君 任达飞 洪峰[1] 张平 吴迪 郑佳敏 詹江南 黄艳[3] HU Jun;REN Da-fei;HONG Feng;ZHANG Ping;WU Di;ZHENG Jia-min;ZHAN Jiang-nan;HUANG Yan(School of Public Health,Guizhou Medical University,Key Laboratory of Environmental Pollution Monitoring and Disease Control,Ministry of Education,Guiyang Guizhou 550025,China;不详)

机构地区：[1]贵州医科大学公共卫生与健康学院环境污染与疾病监控教育部重点实验室,贵州贵阳550025 [2]铜仁市疾病预防控制中心 [3]贵州省疾病预防控制中心

出　　处：《江苏预防医学》2024年第1期96-99,共4页Jiangsu Journal of Preventive Medicine

基　　金：贵州省科技厅[黔科合支撑2021一般027]贵州省新型冠状病毒肺炎分子流行病学特征及防控策略研究。

摘　　要：目的了解新冠病毒感染大流行后铜仁市疾控机构工作人员感染情况及疫苗保护效果。方法2023年2月,在铜仁市、区(县)疾控机构开展网络问卷调查,查询核酸检测和预防接种记录,分析在职职工感染特征及疫苗接种等情况。结果获得682份有效问卷,有效应答率93.16%,总体感染率88.71%;不同性别感染率差异有统计学意义(χ^(2)=21.58,P<0.01);症状主要为发热、乏力、全身酸痛等;确诊病例乏力、头晕/头痛、咽部干痒、味觉减退率均高于疑似病例,差异均有统计学意义(P值均<0.05);有、无吸烟史人群新冠感染率分别为77.24%、91.81%,差异有统计学意义(χ^(2)=24.18,P<0.01);感染组与未感染组之间不同新冠疫苗接种剂次、末次疫苗接种距今时间、疫苗加强接种方式差异均有统计学意义(P值均<0.01)。结论各级疾控机构工作人员新冠感染率较高,新冠疫苗加强接种剂次、序贯接种可以降低感染的风险。应继续推进加强第2剂接种,提高接种率,树立人群牢固的免疫屏障。Objective To investigate the prevalence of SARS-CoV-2 infections and protective effect of COVID-19 vaccines among workers in disease control and prevention institutions following the COVID-19 pandemic.Methods An internet-based questionnaire survey was performed in city-and county-level disease control and prevention institutions in Tongren City in February,2023.The records of nucleic acid tests and vaccinations were retrieved,and the characteristics of SARS-CoV-2 infections and vaccination were analyzed among in-service employees.Results A total of 682 valid questionnaires were recovered,with an effective response rate of 93.2%.The overall prevalence of SARS-CoV-2 infections was 88.71%among the respondents,and there was a gender-specific prevalence rate of SARS-CoV-2 infections(χ^(2)=21.58,P<0.01).The symptoms of SARS-CoV-2 infections mainly included fever,weakness and systemic soreness and pain,and the proportions of weakness,dizziness/headache,throat dryness and itching and hypogeusia were all higher a-mong confirmed cases than among suspected cases(all P values<0.05),and there was a significant difference in the prevalence of SARS-CoV-2 infections between respondents with and without a history of smoking(77.24%vs.91.81%;χ^(2)=24.18,P<0.01).In addi-tion,there were significant differences between respondents with and without SARS-CoV-2 infections in terms of doses of different COV-ID-19 vaccines,duration from the last vaccination and delivery routes of booster vaccination(all P values<0.01).Conclusions There is a high rate of SARS-CoV-2 infections among worker in disease control and prevention institutions at different levels,and booster doses for COVID-19 vaccination and sequential vaccination may reduce the risk of SARS-CoV-2 infections.A second booster dose and improved coverage of COVID-19 vaccination are strongly recommended to build a solid immune barrier in humans.

关 键 词：疾控机构工作人员 新冠病毒感染 流行病学特征 疫苗接种 

分 类 号：R186[医药卫生—流行病学]