2010—2022年连云港市恙虫病流行病学特征分析  

Epidemiological characteristics of scrub typhus in LianyungangCity in 2010-2022

作　　者：郑艳泽 陈玉格 张嘉陵[1] 吕福荣 支明 李海朋[1] 赵兴[1] 周安莲 许雷[1] ZHENG Yanze;CHEN Yuge;ZHANG Jialing;LYU Furong;ZHI Ming;LI Haipeng;ZHAO Xing;ZHOU Anlian;XU Lei(Lianyungang City Center for Disease Control and Prevention,Lianyungang,Jiangsu 222003,China;Kangda College of Nanjing Medical University,Lianyungang,Jiangsu 222000,China)

机构地区：[1]江苏省连云港市疾病预防控制中心,江苏连云港222003 [2]南京医科大学康达学院,江苏连云港222000

出　　处：《公共卫生与预防医学》2024年第3期95-98,共4页Journal of Public Health and Preventive Medicine

基　　金：2023年连云港市卫生健康面上科技项目(202338);连云港市新冠肺炎病例随访研究(Z2020078)。

摘　　要：目的掌握连云港市恙虫病流行病学特征,为恙虫病防控工作提供科学依据。方法恙虫病人群及地区分布采用描述性流行病学方法,季节性特征分析采用集中度法、圆分布法,发病趋势分析采用Joinpoint回归模型。结果2010—2022年恙虫病报告发病率0.95/10万,男性发病率0.77/10万,低于女性发病率1.12/10万(χ^(2)=18.89,P<0.05);60~74岁年龄组发病率3.38/10万,45~74岁组发病总数416例(74.95%),职业分布以农民为主448例(80.72%);报告发病数前3位地区(依次东海县、赣榆区、灌南县)累计报告416例,占全市报告总数74.95%;集中度M=0.9408,恙虫病发病具有严格季节性;圆分布结果,α=-62.3728,S=20.8960,即发病高峰日10月29日、高峰期10月7日至11月19日;2010—2022年发病率平均年度变化百分比(average annual percent change,AAPC)=13.70%、95%CI:-8.62%~41.48%,发病率呈上升趋势(t=1.15,P=0.249)。结论恙虫病发病具有严格季节性特征,历年发病率呈上升趋势,需加强监测并采取各项干预措施,降低恙虫病发病风险。Objective To understand the epidemiological characteristics of scrub typhus disease and to provide a scientific basis for the prevention and control of scrub typhus disease.Methods Descriptive epidemiological methods were used to analyze the population and regional distribution of scrub typhus.Seasonal characteristics were analyzed using concentration method and circular distribution method,and incidence trend was analyzed using joinpoint regression model.Results The annual incidence rate of scrub typhus was 0.95/100000 from 2010 to 2022.The incidence rate of male was 0.77/100000,lower than that of female 1.12/100000(χ^(2)=18.89,P<0.05).The incidence rate of the 60-74 years old group was 3.38/100000,and the total number of cases in the age group 45-74 years was 416(74.95%).Occupational distribution was mainly among farmers,with 448 cases(80.72%).The top three regions with the highest number of reported cases(in order:Donghai County,Ganyu District,and Guannan County)reported a total of 416 cases,accounting for 74.95%.Concentration ratio was M=0.9408,and the incidence of scrub typhus disease was strictly seasonal.Circular distribution results showed a=-62.3728,S=20.8960.The circular distribution results indicated that the peak day was October 19th,and the peak period was between October 7 to December 19.The average annual percentage change(AAPC)of the incidence rate from 2010 to 2022 was 13.70%,95%CI:-8.62%~41.48%,and the incidence rate showed an upward trend(t=1.15,P=0.249).Conclusion The incidence of scrub typhus disease is strictly seasonal,and the incidence rate over the years shows an upward trend.It is necessary to strengthen monitoring and take various intervention measures to reduce the risk of scrub typhus disease.

关 键 词：恙虫病 流行病学特征 集中度法 圆分布法 Joinpoint回归模型 自然疫源性疾病 

分 类 号：R181[医药卫生—流行病学]