无锡地区病毒性心肌炎感染及流行病学特征分析  

Infections and epidemiological characteristics of viralmyocarditis in Wuxi Region

作　　者：徐泽 李婷 曹文婷 XU Ze;LI Ting;CAO Wenting(Department of Laboratory,Wuxi Center for Disease Control and Prevention,Wuxi,Jiangsu 214023,China;Department of Laboratory Medicine,Wuxi Eighth People′s Hospital,Wuxi,Jiangsu 214000,China)

机构地区：[1]江苏省无锡市疾病预防控制中心检验科,江苏无锡214023 [2]江苏省无锡市第八人民医院检验科,江苏无锡214000

出　　处：《公共卫生与预防医学》2024年第3期107-110,共4页Journal of Public Health and Preventive Medicine

基　　金：无锡市卫生健康委科研项目(M202158)。

摘　　要：目的对无锡地区病毒性心肌炎的流行情况与病理学特征展开分析,为病毒性心肌炎的流行病学研究提供参考依据。方法纳入2013—2022年确诊的8000例病毒性心肌炎患者,对其基本资料和感染情况进行统计学分析,检测患者血清中柯萨奇B组病毒核酸。结果病毒性心肌炎以柯萨奇B组病毒感染为主,确诊的阳性率为69.24%,感染病毒的型别以B3、B4为主,分别为29.31%、33.87%。病毒性心肌炎的感染随年龄变化,儿童的阳性率更高,为69.29%,不同年龄组别差异存在统计学意义(X^(2)=1210.344,P<0.001)。男性柯萨奇B族病毒感染率为38.21%,女性为31.03%,差异有统计学意义(X^(2)=155.032,P<0.001)。结论无锡地区近10年来病毒性心肌炎患者儿童感染率高于成年人,且男性的发生情况更高,以B3和B4的柯萨奇B组病毒感染为主,需要加大儿童和青年男性的预防力度。Objective To analyze the epidemic situation and pathological characteristics of viral myocarditis in Wuxi region,laying the foundation for epidemiological research on viral myocarditis.Method A total of 8000 patients with viral myocarditis from 2013 to 2022 were included.The basic data and infection status of patients diagnosed with viral myocarditis within 10 years were statistically analyzed,and the serum of the patients was tested for Coxsackie B virus nucleic acid.Results Viral myocarditis is mainly caused by Coxsackie B virus infection,with a confirmed positive rate of 69.24%.The main types of infected viruses are B3 and B4,with 29.31% and 33.87%,respectively.The infection of viral myocarditis varies with age,and the positive rate in children is higher at 69.29%,with statistical differences among different age groups(X^(2)=1210.344,P<0.001).The infection rate of Coxsackie B virus was 38.21%in males and 31.03% in females,with a statistically significant difference(X^(2)=155.032,P<0.001).Conclusion In the past 10 years,the infection rate of suspected viral myocarditis in children in Wuxi region has been higher than that in adults,and the incidence of COVID-19 B group virus infection is higher in men,with B3 and B4 being the main cases.It is necessary to increase prevention efforts in children and young men.

关 键 词：病毒性心肌炎 B族柯萨奇病毒 细小病毒B19 流行病学特征 

分 类 号：R181[医药卫生—流行病学]