高压氧辅助治疗对糖尿病患者血糖影响的Meta分析  

Meta-analysis of the effect of hyperbaric oxygen therapy on blood glucose in diabetic patients

作　　者：代艳芬 董安华[2] 仲蓓[1] 万金娥[1] 林绍梅 谷健[1] Dai Yanfen;Dong Anhua;Zhong Bei;Wan Jine;Lin Shaomei;Gu Jian(Department of Hyperbaric Oxygen,Affiliated Hospital of Qingdao University,Qingdao 266003,China;Department of Organ Transplantation,Affiliated Hospital of Qingdao University,Qingdao 266003,China)

机构地区：[1]青岛大学附属医院高压氧科,青岛266003 [2]青岛大学附属医院器官移植科,青岛266003

出　　处：《中华航海医学与高气压医学杂志》2024年第1期36-40,共5页Chinese Journal of Nautical Medicine and Hyperbaric Medicine

摘　　要：目的分析高压氧(HBO)辅助治疗糖尿病时对血糖的影响。方法检索PubMed、Embase、CBM、CNKI、VIP和万方数据库(WAN-FANG DATA)等数据库,时间限定为自建库至2022年1月。收集高压氧联合常规药物治疗糖尿病的随机对照试验(RCTs)。3名研究者独立筛选收集到的RCTs,提取相关数据、评估文献质量。应用RevMan 5.3软件进行Meta分析。结果本研究共纳入8个RCTs,Meta分析结果显示,与对照组相比,高压氧联合常规治疗组患者的空腹血糖、餐后2 h血糖、糖化血红蛋白明显降低(P≤0.01)。结论高压氧辅助治疗糖尿病可降低患者的血糖水平,为高压氧的临床应用提供证据。Objective To analyze the effect of hyperbaric oxygen(HBO)therapy on blood glucose in the treatment of diabetes mellitus.Methods The articles were retrieved from PubMed,Embase,CBM,CNKI,VIP,and WANFANG DATA with the publishment time from the establishment of the database to January 2022.The randomized controlled trials(RCTs)of hyperbaric oxygen combined with conventional medication treatment of diabetes mellitus were collected.Three researchers independently screened the RCTs,extracted relevant data,and evaluated the quality of the trial.Meta-analysis was performed using RevMan 5.3.Results A total of eight RCTs were included in this study.The results of meta-analysis showed that fasting blood glucose(FBG),2-hour postprandial blood glucose(PBG),and HbA1c in the observation group were significantly decreased compared to those in control group(P≤0.01).Conclusion Hyperbaric oxygen can reduce blood glucose level in patients with diabetes mellitus,providing evidence for clinical application of hyperbaric oxygen.

关 键 词：糖尿病 高压氧 META分析 

分 类 号：R587.1[医药卫生—内分泌]