海军飞行人员高尿酸血症患病状况及影响因素分析  

Prevalence and influencing factors of hyperuricemia in naval aviation personnel

作　　者：宋平 范茂丹 李峰 苟昊林 俞秀霞 周磊 Song Ping;Fan Maodan;Li Feng;Gou Haolin;Yu Xiuxia;Zhou Lei(Naval Medical Center,Naval Medical University,Shanghai 200052,China;Third Rehabilitation Zone,Hangzhou Rehabilitation Centre for Special Duty Servicemen of the PLA Air Force,Hangzhou 31002,China;Unit 92730 of the PLA,Sanya 572016,China)

机构地区：[1]海军军医大学海军特色医学中心,上海200052 [2]空军杭州特勤疗养中心疗养三区,杭州310002 [3]解放军92730部队,三亚572016

出　　处：《中华航海医学与高气压医学杂志》2024年第1期46-50,共5页Chinese Journal of Nautical Medicine and Hyperbaric Medicine

摘　　要：目的了解海军飞行人员血尿酸水平及高尿酸血症检出情况,调查分析高尿酸血症发病影响因素。方法收集717例海军飞行人员人口学信息、生活方式资料,并回顾性分析其年度体检数据,根据血尿酸水平分为正常组及高尿酸血症组,计算海军飞行人员高尿酸血症检出率,了解发病特征。通过χ^(2)检验、Logistic回归分析高尿酸血症飞行人员发病影响因素。结果717名海军飞行人员中,共检出高尿酸血症195例(195/717,27.20%),纳入高尿酸血症组,血尿酸水平(473.70±48.35)μmol/L;血尿酸正常522例(522/717,72.80%),纳入正常尿酸组,血尿酸水平(350.10±42.73)μmol/L。χ^(2)检验结果显示,正常尿酸组和高尿酸血症组在饮食、运动、吸烟、饮酒、睡眠等生活习惯,职业累计时间、体重指数、丙氨酸转氨酶、天冬氨酸转氨酶、三酰甘油、胆固醇、低密度脂蛋白胆固醇、空腹血糖等方面的检出率差异有统计学意义(P<0.05)。进一步多因素Logistic回归分析发现,饮食、运动、饮酒、睡眠、三酰甘油、低密度脂蛋白胆固醇是高尿酸血症发病的独立影响因素(P<0.05)。结论海军飞行人员高尿酸血症检出率较高,其发病主要与不良生活习惯、三酰甘油升高、低密度脂蛋白胆固醇升高有关。在进行健康宣教时,应指导其养成少食用海鲜、多食新鲜蔬菜、保持规律运动、戒酒、改善睡眠等良好生活习惯,控制三酰甘油、低密度脂蛋白胆固醇水平,降低高尿酸血症发病率,提高海军飞行人员健康水平。Objective To investigate the level of serum uric acid and the prevalence of hyperuricemia in naval aviation personnel,and analyze the influencing factors of hyperuricemia.Methods The demographic information and lifestyle data of 717 naval aviation personnel were collected,and their annual physical examination data were analyzed retrospectively.According to the blood uric acid level,they were divided into normal group and hyperuricemia group.The detection rate of hyperuricemia in naval aviation personnel was calculated to investigate the characteristics of the prevalence of the disease.The influencing factors of hyperuricemia in naval aviation personnel were analyzed by chi-square test and logistic regression.Results Among the 717 naval aviation personnel,195(195/717,27.20%)were detected as hyperuricemia and were assigned in the hyperuricemia group,with blood uric acid level of(473.70±48.35)μmol/L.A total of 522 cases(522/717,72.80%)with normal blood uric acid were assigned in the normal uric acid group,with blood uric acid level of(350.10±42.73)μmol/L.The results of chi-square test showed that there were statistically significant differences between the normal uric acid group and the hyperuricemia group in the factors of living habits,such as diet,physical exercise,smoking,drinking alcohol,and sleep quality,and cumulated occupational time,body mass index,alanine aminotransferase,aspartate aminotransferase,triacylglycerol,cholesterol,low density lipoprotein cholesterol,and fasting blood glucose(P<0.05).Multivariate logistic regression analysis showed that diet,physical exercise,alcohol drinking,sleep quality,triglyceride,and low-density lipoprotein cholesterol were independent influential factors of hyperuricemia(P<0.05).Conclusion The detection rate of hyperuricemia in naval aviation personnel is high,and its occurrence is mainly related to unhealthy living habits,elevated triacylglycerol,and elevated low density lipoprotein cholesterol.It is recommended to emphasize forging good living habits such as eating

关 键 词：高尿酸血症 尿酸 检出率 横断面研究 影响因素 

分 类 号：R835.2[医药卫生—航空、航天与航海医学]