应用活体共聚焦显微镜观察糖尿病患者的角膜细胞  

Observation of corneal cell in diabetic patients using in vivo confocal microscopy

作　　者：孟令蕊 陈文倩 高艺 叶子 李朝辉 Meng Lingrui;Chen Wenqian;Gao Yi;Ye Zi;Li Zhaohui(Senior Department of Ophthalmology,the Third Medical Center,Chinese PLA General Hospital,Beijing 100039,China)

机构地区：[1]中国人民解放军总医院第三医学中心眼科医学部,北京市100039

出　　处：《国际眼科杂志》2024年第5期664-670,共7页International Eye Science

摘　　要：活体角膜共聚焦显微镜是一种无创、快速且全层面的技术,可以实时、动态地观察角膜组织的所有层面。共聚焦显微镜可以通过直接可视化检查角膜不同层面的形态和细胞密度。随着糖尿病患病率的不断上升,眼部并发症已经变得越发常见,并引起眼科临床工作者和科研工作者越来越多的兴趣和逐渐深入的研究。文章旨在通过采用活体角膜共聚焦显微镜观察糖尿病患者角膜组织各层的研究进展进行综述。In vivo confocal microscopy of the cornea is a non-invasive,rapid,and comprehensive technique for real-time,dynamic observation of all layers of the cornea.Confocal microscopy allows the examination of the morphology and cell density in the different layers of the cornea through direct visualization.With the increasing prevalence of diabetes,ocular complications have become common and have garnered more interest and in-depth research from clinical and scientific communities.This paper provides a comprehensive review of research progress made using in vivo confocal microscopy to observe various layers of cornea tissue in diabetic patients.

关 键 词：共聚焦显微镜 糖尿病 角膜上皮 基质细胞 内皮细胞 

分 类 号：R587.2[医药卫生—内分泌] R77[医药卫生—内科学]