Chinese herbal medicine Ginkgo biloba L.preparations for ischemic stroke:An overview of systematic reviews and meta-analyses  

作　　者：Tian-tian Meng Ya-ping You Min Li Jian-bo Guo Xin-bin Song Jing-yi Ding Xiao-long Xie An-qi Li Shang-jin Li Xiang-jun Yin Peng Wang Zhe Wang Bao-liang Wang Qing-yong He 

机构地区：[1]Department of Cardiology,Guang'anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100032,China [2]Department of Rehabilitation,Dongfang Hospital,Beijing University of Chinese Medicine,Beijing 100071,China [3]School of Chemistry and Chemical Engineering,Shanghai Jiao Tong University,Shanghai 200240,China [4]School of Chinese Medicine,the University of Hong Kong,Hong Kong,China [5]Graduate School,Henan University of Chinese Medicine,Zhengzhou 450008,Henan Province,China [6]Department of Acupuncture and Moxibustion,Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100010,China [7]Department of Cardiology,Guang’anmen Hospital,China Academy of Chinese Medical Sciences,Zhengzhou 450008,Henan Province,China [8]School of Integrated Traditional Chinese and Western Medicine,Southwest Medical University,Hangzhou 310053,Zhejiang Province,China [9]School of Basic Medical Sciences,Zhejiang Chinese Medical University,Hangzhu 310053,Zhejang Province,China [10]Department of Neurology,the First Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou 450003,Henan Province,China

出　　处：《Journal of Integrative Medicine》2024年第2期163-179,共17页结合医学学报（英文版）

基　　金：supported by the Traditional Chinese Medicine Ancient Book Documents and Characteristic Technology Inheritance Project of the National Administration of Traditional Chinese Medicine(No.GZY-KJS-2020-079);the Research and Transformation Application of Clinical Characteristic Diagnosis and Treatment Techniques in the Capital(No.Z221100007422081);the National Famous Old TCM Experts Baoliang Wang Inheritance Studio Construction Program,State TCM Office Human Education Letter(No.[2022]75)。

摘　　要：Background:Ginkgo biloba L.preparations(GBLPs)are a class of Chinese herbal medicine used in the adjuvant treatment of ischemic stroke(IS).Recently,several systematic reviews(SRs)and meta-analyses(MAs)of GBLPs for IS have been published.Objective:This overview aims to assess the quality of related SRs and MAs.Search strategy:Pub Med,Embase,Cochrane Library,Web of Science,Chinese Biological Medicine,China National Knowledge Infrastructure,Wanfang,and Chinese Science and Technology Journals databases were searched from their inception to December 31,2022.Inclusion criteria:SRs and MAs of randomized controlled trials(RCTs)that explored the efficacy of GBLPs for patients with IS were included.Data extraction and analysis:Two independent reviewers extracted data and assessed the methodological quality,risk of bias(ROB),reporting quality,and credibility of evidence of the included SRs and MAs using A Measurement Tool to Assess Systematic Reviews 2(AMSTAR 2),Risk of Bias in Systematic Reviews(ROBIS),the Preferred Reporting Items for Systematic Reviews and Meta-analyses(PRISMA),and the Grading of Recommendations Assessment,Development and Evaluation(GRADE),respectively.Additionally,descriptive analysis and data synthesis were conducted.Results:Twenty-nine SRs/MAs involving 119 outcomes were included in this review.The overall methodological quality of all SRs/MAs was critically low based on AMSTAR 2,and 28 had a high ROB based on the ROBIS.According to the PRISMA statement,the reporting items of the included SRs/MAs are relatively complete.The results based on GRADE showed that of the 119 outcomes,8 were rated as moderate quality,24 as low quality,and 87 as very low quality.Based on the data synthesis,GBLPs used in conjunction with conventional treatment were superior to conventional treatment alone for decreasing neurological function scores.Conclusion:GBLPs can be considered a beneficial supplemental therapy for IS.However,because of the low quality of the existing evidence,high-quality RCTs and SRs/MAs are warranted t

关 键 词：STATEMENT synthesis ALONE 

分 类 号：R277.7[医药卫生—中医学]