石墨炉原子吸收法测定枸橼酸铁铵中的铬元素  

Determination of chromium in Ferric ammonium citrate by Graphite furnace atomic absorption spectrometry

作　　者：黄俊 HUANG Jun(NMPA Key Laboratory for Quality Monitoring of Narcotic Drugs and Psychotropic Substances,Chongqing Institute for Food and Drug Control,Chongqing,401121 P.R.China)

机构地区：[1]重庆市食品药品检验检测研究院国家药品监督管理局麻醉精神药品质量监测重点实验室,重庆401121

出　　处：《华西药学杂志》2024年第2期203-205,共3页West China Journal of Pharmaceutical Sciences

摘　　要：目的采用石墨炉原子吸收光谱法测定枸橼酸铁铵中的铬(Cr)元素。方法采用硝酸消解,灰化温度1500℃,原子化温度2300℃。结果测定Cr的检出限为0.26 ng·mL^(-1),r为0.9990,RSD=1.85%;平均回收率为96.92%(RSD=2.77%,n=9)。结论所用方法灵敏度高、选择性好,可用于枸橼酸铁铵中Cr的测定。OBJECTIVE To detect chromium in Ferric ammonium citrate by graphite furnace atomic absorption spectrometric method.METHODS S Nitric acid was selected as the digestive acid.The ashing temperature was 1500 C,and the atomization temperature was 2300℃.RESULTS The method exhibited a detection limit of 0.26 ng mL^(-1) with r of 0.9990.RSD of precisien test was 1.85%.The average recovery was 96.92%,RSD of recovery was 2.77%(n=9).CONCLUSION The method is accurate with high sensitivity and specificity,and suitable for the determination of chromium in Ferric ammonium citrate.

关 键 词：石墨炉 原子吸收法 枸橼酸铁铵 铬 重金属 含量测定 原料药 缺铁性贫血 

分 类 号：R917[医药卫生—药物分析学]