The effect of carbapenem resistance in Klebsiellae on infection outcomes in animals and birds  

作　　者：Bhoj R Singh Abhijit M Pawde 

机构地区：[1]Division of Epidemiology,ICAR-Indian Veterinary Research Institute,Bareilly 243122,India [2]Wildlife Cetre,ICAR-Indian Veterinary Research Institute,Bareilly 243122,India

出　　处：《Infectious Diseases Research》2024年第2期12-14,共3页传染病研究（英文）

摘　　要：It is often said that the emergence of antimicrobial drug resistance(AMR)in pathogens is the major cause of mortality.In the present study,clinical microbiology data on infections caused by Klebsiella pneumoniae strains and their antimicrobial drug resistance specifically to carbapenems retrieved from Clinical Epidemiology database of the Institute were analysed to determine the impact of carbapenem resistance in Klebsiellae isolated from the clinical samples of veterinary cases and outcome of the infection because in a few recent reports it is claimed that the presence of carbapenem-resistant Klebsiellae is associated with higher mortality in humans due to Klebsiella infections.The retrospective analysis of Klebsiella infections in animals and birds revealed that 21.8%of K.pneumoniae causing pneumonic or septicemic infections were carbapenem-resistant but the carbapenem resistance was not associated with increased numbers of deaths or recovery.It may be probably due to the fact that carbapenem drugs were not used for the treatment of infected animals and carbapenem resistance may not be associated with the lethality potential of Klebsiellae.

关 键 词：Klebsiella pneumoniae Klebsiella oxytoca Klebsiella aerogenes ABORTIONS 

分 类 号：R51[医药卫生—内科学]