肾脏IVIM最佳水化状态及稳定性、可重复性研究  

Study on the optimal hydration state,stability and repeatability of renal IVIM

作　　者：魏学哲 王文娟[2] 沈婷婷[3] 尹金凤 郭君岩 韩雨[3] 刘金刚[3] WEI Xuezhe;WANG Wenjuan;SHEN Tingting;YIN Jinfeng;GUO Junyan;HAN Yu;LIU Jingang(School of Medical Imaging,Weifang Medical University,Weifang 261053,China;Department of Radiology,Weifang People's Hospital,Weifang 261041,China;Center for Medical Imaging,Affiliated Hospital of Weifang Medical University,Weifang 261031,China)

机构地区：[1]潍坊医学院医学影像学院,山东潍坊261053 [2]山东省潍坊市人民医院放射科,山东潍坊261041 [3]潍坊医学院附属医院影像中心,山东潍坊261031

出　　处：《医学影像学杂志》2024年第3期74-78,共5页Journal of Medical Imaging

基　　金：山东省高等学校科技计划项目(编号:J18KA284);山东省潍坊市科技发展计划项目(编号:2022YX049);潍坊医学院附属医院医学研究培育基金项目(编号:2022wyfyzzjj09)。

摘　　要：目的探讨行肾脏体素内不相干运动成像(intravoxel incoherent motion,IVIM)检查的最佳水化状态,并分析检查结果的稳定性和可重复性。方法选取健康成年人志愿者40例,每例志愿者均分别在禁饮食12 h、禁饮食4 h及水利尿三种状态下行肾脏IVIM检查;其中36例志愿者在间隔半年后,在禁饮食4 h状态下重复行肾脏IVIM检查。结果三种不同水化状态下,肾皮质(F=1.870,P=0.163)及髓质(F=0.579,P=0.562)D值间的差异无统计学意义,肾皮质(F=0.188,P=0.829)及髓质(F=0.008,P=0.992)D*值间的差异均无统计学意义,肾皮质(F=1.317,P=0.216)及髓质(F=0.336,P=0.715)f值间的差异均无统计学意义。结论水化状态不影响肾脏IVIM的检查结果,肾脏IVIM检查有很高的稳定性和可重复性;肾脏IVIM检查可以监测正常肾脏的微循环状态及血流灌注状态。Objective To explore the optimal hydration state of by IVIM kidney,and to analyze the stability and repeatabil‐ity of the results.Methods Forty volunteers underwent kidney IVIM examination in three states of hydration.The hydration states included abstaining from food and water for 12 hours,abstaining from food and water for 4 hours and water diuresis.After half a year,there were thirty-six volunteers repeating kidney IVIM examination,demanding them to abstain from food and water for 4 hours.Results(1)The differences between cortical(F=1.870,P=0.163)and medullary(F=0.579,P=0.562)D value of three hydration states were not statistically significant;The differences between cortical(F=0.188,P=0.829)and medullary(F=0.008,P=0.992)D*value of three hydration states were not statistically significant;The differences between cortical(F=1.317,P=0.216)and medullary(F=0.336,P=0.715)f value of three hydration states were not statistically significant.Conclu⁃sion Hydration states could not affect kidney IVIM.Kidney IVIM examination had high stability,so the results were reliable.Kidney IVIM could detect the normal renal microcirculation status and blood flow perfusion.

关 键 词：磁共振成像 体素内不相干运动 肾脏 水化状态 可重复性 

分 类 号：R334.1[医药卫生—人体生理学] R445.2[医药卫生—基础医学]