便携式多生理参数检测仪的设计  

Design of a portable multi-physiological parameter detector

作　　者：周延顺 于致远 郭永生 郭圣文 ZHOU Yanshun;YU Zhiyuan;GUO Yongsheng;GUO Shengwen(School of Material Science and Engineering,South China University of Technology,Guangzhou 510006,China;Guangzhou Zhongkang Xianjue Health Technology Co.,Ltd.,Guangzhou 510006,China;School of Automation Science and Engineering,South China University of Technology,Guangzhou 510640,China)

机构地区：[1]华南理工大学材料科学与工程学院,广东广州510006 [2]广州中康先觉健康科技有限责任公司,广东广州510006 [3]华南理工大学自动化科学与工程学院,广东广州501640

出　　处：《中国医学物理学杂志》2024年第4期486-494,共9页Chinese Journal of Medical Physics

基　　金：广州市重点研发计划(2023B03J1335)。

摘　　要：为了检测人体的电阻抗、血氧、心率和体温等生理参数,设计一种头戴式的多功能便携检测仪。该设备针对现有阻抗检测设备的激励频率范围窄、精度不足和检测耗时长等问题进行优化:采用四电极阻抗检测方案,通过直接数字频率合成器和Howland电流源生成正弦激励电流流经人体,使用ADI公司的AD8302增益相位检波器芯片和配套算法计算得到人体电阻抗的幅值和相位,有效提高检测的准确性和效率。为了进一步减小系统误差,设计模拟开关电路并配合高精度采样电阻和相移电容实现系统参数的自校准。实验结果表明,在10 kHz~1 MHz的检测频率范围内,阻抗幅值和相位的平均检测误差分别小于0.5%和0.59°,最大检测误差分别小于1.54%和1.38°,显示出比基于TI公司AFE4300芯片的阻抗检测方案更优的性能。此外,设备还整合了血氧、心率和体温的检测模块。人体实验验证了其在准确和有效检测多种生理参数方面的优越性。A novel portable head-mounted detector is designed to obtain the multi-physiological parameters,such as electrical impedance,blood oxygen,heart rate and body temperature.To address the issues such as narrow excitation frequency range,low accuracy and long detection time in the existing impedance detectors,the developed detector adopts 4-electrode measurement scheme,using a direct digital frequency synthesizer and Howland current source to generate sinusoidal excitation currents through the human body,employing AD8302 gain phase detector chip from Analog Devices Inc.,along with accompanying algorithms to calculate the amplitude and phase angle of the body's impedance,which significantly enhances detection accuracy and efficiency.To further minimize system errors,an analog switch circuit is designed in conjunction with high-precision sampling resistors and phase-shift capacitors for system parameter self-calibration.Experimental results reveal that within the detection frequency range of 10 kHz to 1 MHz,the average detection errors for impedance magnitude and phase are less than 0.5% and 0.59°,respectively,with maximum detection errors less than 1.54% and 1.38°,respectively,demonstrating superior performance than impedance detection schemes based on the TI company's AFE4300 chip.Additionally,the device integrates modules for the detection of blood oxygen,heart rate,and temperature.Human body experiments also verified its superiority in accuracy and effectiveness of multiphysiological parameter detection.

关 键 词：头戴式检测仪 生物阻抗 相位 四电极检测方案 多生理参数检测 

分 类 号：R318[医药卫生—生物医学工程] TH79[医药卫生—基础医学]