中医辨证结合中西医治疗PCOS疗效及对患者性激素、脂代谢和卵巢的影响  

Effect of the dialectical traditional Chinese medicine combined with the western medicine for treating patients with polycystic ovary syndrome and their influence on the sex hormones levels,the lipid metabolism and the ovary function of the patients

作　　者：夏明明 黄平 XIA MingMing;HUANG Ping(The First Affiliated Hospital,Zhejiang University of traditional Chinese Medicine,Hangzhou,Zhejiang Province,310000;The Second Affiliated Hospital of Zhejiang University of traditional Chinese Medicine)

机构地区：[1]浙江中医药大学附属第一医院,杭州310000 [2]浙江中医药大学附属第二医院

出　　处：《中国计划生育学杂志》2024年第4期774-777,783,共5页Chinese Journal of Family Planning

摘　　要：目的:探讨中医辨证结合中西医治疗多囊卵巢综合征(PCOS)疗效及对性激素、脂代谢和卵巢的影响。方法:选择本院2022年5月-2023年5月收治的PCOS患者90例,随机数字表法分为两组各45例,西医组常规西药治疗,中西医组在西医组治疗基础上采用基于中医辨证的中药治疗,对比两组临床疗效、性激素水平、脂代谢指标、卵巢情况。结果:中西医组临床治疗总有效率(88.9%)高于西医组(68.9%);治疗后两组促卵泡激素(FSH)、睾酮(T)、黄体生成素(LH)、卵泡数目、卵巢体积、总胆固醇(TC)、甘油三酯(TG)、空腹胰岛素(FINS)水平均降低,且中西医组FSH(4.79±0.68 mU/ml)、T(2.46±1.14 ng/ml)、LH(11.29±1.47 ng/ml)水平低于西医组(5.22±1.09 mU/ml、3.24±1.23 ng/ml、13.44±2.36 ng/ml),卵泡数目(7.21±1.25个)、卵巢体积(8.54±1.35 cm^(3))低于西医组(9.46±1.49个、10.21±1.62 cm^(3)),TC、TG、FINS水平低于西医组(均P<0.05)。结论:中医辨证结合中西医治疗PCOS可提升临床疗效,进一步改善患者性激素、脂代谢水平和卵巢功能。Objective:To investigate the therapeutic effect of the dialectical traditional Chinese medicine combined with the western medicine for treating patients with polycystic ovary syndrome(PCOS),and to study their influence on the sex hormones levels,the lipid metabolism and the ovary function of the patients.Methods:A total of 90 patients with PCOS were selected and were divided into two groups(45 cases in each group)according to random number table method from May 2022 to May 2023.The patients in the study group were given the dialectical traditional Chinese medicine combined with the western medicine,and the patients in the control group were given western medicine treatment alone.The clinical efficacy,the sex hormone levels,the lipid metabolism indexes levels and the ovarian conditions of the patients were compared between the two groups.Results:The total effective rate(88.9%)of the patients in the study group was significantly higher than that(68.9%)of the patients in the control group.After treatment,the levels of follicle-stimulating hormone(FSH),testosterone(T),luteinizing hormone(LH),total cholesterol(TC),triglyceride(TG)and fasting insulin(FINS),and the number of follicles and the ovarian volume of the patients in the two groups had decreased significantly.The levels of FSH(4.79±0.68 mU/ml),T(2.46±1.14ng/ml)and LH(11.29±1.47 ng/ml)of the patients in the study group were significantly lower than those(5.22±1.09 mU/ml,3.24±1.23 ng/ml and 13.44±2.36ng/ml)of the patients in the control group.The number of follicles(7.21±1.25)and the ovarian volume(8.54±1.35 cm^(3))of the patients in the study group were significantly lower than those(9.46±1.49 and 10.21±1.62 cm^(3))of the patients in the control group.The levels of TC,TG and FINS of the patients in the study group were significantly lower than those of the patients in the control group(all P<0.05).Conclusion:The dialectical traditional Chinese medicine combined with the western medicine for treating the patients with PCOS can increase their clinical ef

关 键 词：多囊卵巢综合征 中医辨证治疗 中西医结合 性激素 脂代谢指标 卵巢功能 

分 类 号：R711.75[医药卫生—妇产科学]