孕妇孕晚期生殖道GBS感染对胎膜早破、妊娠结局影响  

Group B streptococcus infection status in genital tract of pregnant women during the third trimester of pregnancy and its influence on the premature rupture of membranes and the pregnancy outcomes

作　　者：刘洋 马晓丹 吴云[1] 马铟[1] LIU Yang;MA Xiaodan;WU Yun;MA Yin(Bengbu First People's Hospital,Bengbu,Anhui Province,233000)

机构地区：[1]安徽省蚌埠市第一人民医院,233000

出　　处：《中国计划生育学杂志》2024年第4期866-868,873,共4页Chinese Journal of Family Planning

摘　　要：目的:院内妊娠晚期孕妇生殖道B族链球菌(GBS)感染情况调查并探究对胎膜早破、妊娠结局的影响。方法:选取2021年6月-2023年7月于本院定期产前检查的妊娠晚期孕妇3970例GBS感染检测,根据感染情况分为感染组和非感染组,比较两组胎膜早破发生率及妊娠不良结局。结果:3970例孕妇中103例GBS感染,感染率2.6%,纳入感染组,非感染孕妇中随机选取103例纳入非感染组;感染组年龄≤30岁组感染率(68.0%)高于>30~35岁组及>35岁组,感染组胎膜早破发生率(18.5%)高于非感染组(4.9%),绒毛膜羊膜炎(6.8%)、新生儿肺炎(13.6%)、胎儿生长发育迟缓(8.7%)、新生儿感染(7.8%)、胎儿宫内窘迫(9.7%)发生率均高于非感染组(0、4.9%、1.0%、1.0%、1.9%)(均P<0.05);两组产妇分娩期发热、新生儿黄疸发生率未见差异(P>0.05)。结论:孕晚期孕妇发生GBS感染增加胎膜早破及不良妊娠结局发生风险,临床应及时采取措施治疗干预。Objective:To investigate the group B streptococcus(GBS)infection status in genital tract of pregnant women during the third trimester of pregnancy,and to study its influence on the premature rupture of membranes and the pregnancy outcomes of the women.Methods:3,970 pregnant women during the third trimester of pregnancy who received regular prenatal examinations were given GBS infection detection from June 2021 to July 2023.These women were divided into group A(women withGBS infection)and group B(women without GBS infection).The rates of the premature rupture of membranes and the adverse pregnancy outcomes of the women were compared between the two groups.Results:Among 3,970 pregnant women,103 women were infected GBS in group A,with an infection rate of 2.6%.Another 103 women who had been randomly selected from the women without GBS infection were included in group B.In group A,the infection rate of the women≤30 years old(68.0%)was significantly higher than that of the women with 30-35 years|old and that of the women>35 years old.The incidence of the premature rupture of membranes(18.5%)of the women in group A was significantly higher than that(4.9%)of the women in group B.The incidences of chorioamnionitis(6.8%),the neonatal pneumonia(13.6%),the fetal growth restriction(8.7%),the neonatal infection(7.8%),the fetal intrauterine distress(9.7%)of the women in group A were significantly higher than those(0,4.9%,1.0%,1.0%and 1.9%)of the women in group B(all P<0.05).There were no significant differences in the incidences of the maternal fever during labor and the neonatal jaundice between the two groups(P>0.05).Conclusion:The GBS infection in genital tract of the pregnant women during the third trimester of pregnancy will increase the incidence of premature rupture of membranes and the risk of adverse pregnancy outcomes.Therefore,the clinical intervention measures should be taken for the women with GBS infection in time.

关 键 词：妊娠晚期 生殖道感染 B族链球菌 胎膜早破 不良妊娠结局 

分 类 号：R714.433[医药卫生—妇产科学]