穿刺冲洗联合头孢呋辛对哺乳期乳腺脓肿患者的应用价值  

Effect of puncture irrigation combined with cefuroxime on adverse reactions in infants with continued breastfeeding by patients with lactating breast abscess

作　　者：史立波 于德海 步玉辉 高桂艳 高路明 姜婷婷 韩晓琳 田洪雨 SHI Libo;YU Dehai;BU Yuhui(Department of Thyroid and Breast Surgery,Cangzhou People’s Hospital,Hebei,Cangzhou 061000,China)

机构地区：[1]河北省沧州市人民医院甲状腺乳腺外科,061000

出　　处：《河北医药》2024年第7期1018-1021,共4页Hebei Medical Journal

基　　金：沧州市科技计划项目(编号:204106005)。

摘　　要：目的探讨穿刺冲洗联合头孢呋辛治疗对哺乳期乳腺脓肿患者继续哺乳婴儿不良反应的影响。方法选取2020年11月至2022年3月就诊的50例哺乳期乳腺脓肿患者作为研究对象,根据随机数字表法分为对照组和观察组,每组25例。对照组采用传统切开引流联合头孢呋辛治疗,观察组采用穿刺冲洗联合头孢呋辛治疗。比较2组临床疗效;2组术中出血量、术后视觉模拟评分法(VAS)评分、换药次数、脓腔愈合时间、瘢痕长度;并发症发生率、复发率;继续哺乳婴儿不良反应发生率。结果观察组临床总有效率(96.00%)显著高于对照组(76.00%),差异有统计学意义(P<0.05);与对照组比较,观察组术中出血量、术后VAS评分、换药次数、脓腔愈合时间、瘢痕长度显著减小(P<0.05);观察组并发症发生率(8.00%)、复发率(4.00%)显著降低与对照组(32.00%、24.00%,P<0.05);观察组继续哺乳率(80.00%)明显高于对照组(28.00%,P<0.05),2组继续哺乳婴儿不良反应发生率比较差异无统计学意义(P>0.05)。结论穿刺冲洗联合头孢呋辛治疗不仅能够有效治疗哺乳期乳腺脓肿,改善临床相关指标,而且还能减少并发症、复发,而继续哺乳不会增加婴儿不良反应,具有较高的临床参考价值。Objective To investigate the adverse reactions of puncture irrigation combined with cefuroxime on adverse reactions in infants with continued breastfeeding by patients with breast abscess.Methods Fifty patients with lactating breast abscess visited our hospital from November 2020 to March 2022 were randomly assigned into the control group(n=25)and the observation group(n=25).All patients were managed by cefuroxime,and those in the control group and the observation group were additionally treatment with traditional incisional drainage and puncture irrigation,respectively.The aim was to compare intraoperative blood loss,postoperative visual analogue scale(VAS),frequency of change medicine,healing time of pus cavity,scar length,complications rate,recurrence rate,adverse reactions in continued breastfeeding.The curative effect was assessed.Results The overall effective rate in the observation group was significantly higher than that in the control group(96.00%vs 76.00%,P<0.05,respectively).Patients in the observation group presented significantly lower intraoperative blood loss,postoperative VAS,frequency of change medicine,healing time of pus cavity,scar length than those of the control group(P<0.05).The rate of complications and recurrence in the observation group were significantly lower than those in the control group(8.00%vs 32.00%,4.00%vs 24.00%,respectively;P<0.05).The rate of continuous breastfeeding in the observation group was significantly higher than that in the control group(80.00%vs 28.00%,P<0.05).None of the incidence of adverse reactions differed significantly between groups(P>0.05).Conclusion For patients with lactating breast abscess,puncture irrigation combined with cefuroxime has an effective therapeutic effect,which can not only improve clinical relevant indicators,but also reduce complications and recurrence.Continuing breastfeeding will not increase adverse reactions in infants,and with high clinical reference value.

关 键 词：穿刺冲洗 头孢呋辛 哺乳期乳腺脓肿 继续哺乳 婴儿 不良反应 

分 类 号：R655.8[医药卫生—外科学]