PCT、hs-CRP、ESR与外周血细胞计数联合在小儿急性细菌性上呼吸道感染筛查中的意义  

Significance of PCT,hs-CRP,ESR and Peripheral Blood Cell Count Combined in Screening for Pediatric Acute Bacterial Upper Respiratory Tract Infection

作　　者：杨安常 YANG Anchang(Department of Pediatrics,Sishui County People's Hospital,Sishui,Shandong Province,273200 China)

机构地区：[1]山东泗水县人民医院儿科,山东泗水273200

出　　处：《系统医学》2024年第4期1-3,8,共4页Systems Medicine

基　　金：国家卫生健康委“十三五”规划全国重点课题(YYwS1352)。

摘　　要：目的 分析降钙素原(Procalcitonin,PCT)、超敏C反应蛋白(High Sensitivity C-Reactive Protein,hsCRP)、红细胞沉降率(Erythrocyte Sedimentation Rate,ESR)与外周血细胞计数联合在小儿急性细菌性上呼吸道感染筛查中的意义。方法 选取2022年1—12月山东泗水县人民医院诊断为小儿急性细菌性上呼吸道感染的100例患儿作为观察组,同时选取本院查体中心的100例健康儿童为对照组。对比两组PCT、hsCRP、ESR与外周血细胞计数,分析PCT、hs-CRP、ESR与外周血细胞计数联合检测对小儿急性细菌性上呼吸道感染的诊断价值。结果 观察组白细胞计数(8.41±1.42)×10^(9)/L、中性粒细胞比例(86.26±5.21)%、中性粒细胞计数(4.29±1.23)×10^(9)/L、hs-CRP(18.34±3.31)mg/L、ESR(18.62±3.95)mm/h、PCT(5.21±1.98)ng/mL明显高于对照组,差异有统计学意义(t=15.889、19.369、12.370、44.844、29.563、24.047,P均<0.05)。4种指标的联合检测其灵敏度、特异度最高,达89.0%,88.0%。结论 PCT、hs-CRP、ESR与外周血细胞计数联合在小儿急性细菌性上呼吸道感染筛查中具有较高的价值。Objective To analyze the significance of procalcitonin(PCT),high sensitivity C-reactive protein(hsCRP),erythrocyte sedimentation rate(ESR) in combination with peripheral blood cell count in the screening of pediatric acute bacterial upper respiratory tract infection.Methods A total of 100 children diagnosed with acute bacterial upper respiratory tract infection in children from the Shandong Sishui County People's Hospital from January to December 2022 were selected as the observation group,and 100 healthy children from the physical examination center of the hospital were selected as the control group.PCT,hs-CRP,ESR and peripheral blood cell counts were compared between the two groups.To analyze the diagnostic value of PCT,hs-CRP,ESR and peripheral blood cell count in children with acute bacterial upper respiratory tract infection.Results In the observation group,leukocyte count(8.41±1.42)×10^(9)/L,neutrophil ratio(86.26±5.21) %,neutrophil count(4.29±1.23)×10^(9)/L,hs-CRP(18.34±3.31) mg/L,ESR(18.62±3.95) mm/h,PCT(5.21±1.98) ng/mL were significantly higher than those of the control group,and the differences were statistically significant(t=15.889,19.369,12.370,44.844,29.563,24.047,all P<0.05).The sensitivity and specificity of the combined detection of the four indexes were the highest,reaching 89.0% and 88.0%.Conclusion The combination of PCT,hs-CRP,ESR and peripheral blood cell count has high value in screening for pediatric acute bacterial upper respiratory tract infection.

关 键 词：降钙素原 超敏C反应蛋白 红细胞沉降率 外周血细胞计数 小儿急性细菌性上呼吸道感染 

分 类 号：R72[医药卫生—儿科]