钙离子通道阻滞剂在慢性疼痛患者中临床应用的研究进展  

Progress in Clinical Application of Calcium Channel Blockers in Patients with Chronic Pain

作　　者：王翼华 王前 张立贇 梁元 WANG Yihua;WANG Qian;ZHANG Liyun;LIANG Yuan(Nanyang First People's Hospital Affiliated to Henan University,Nanyang,Henan Province,471000 China)

机构地区：[1]河南大学附属南阳市第一人民医院,河南南阳471000

出　　处：《系统医学》2024年第4期191-194,共4页Systems Medicine

摘　　要：现代医学将疼痛列为继呼吸、脉搏、血压、体温后的第五生命体征,足见其在人体健康中的重要性。慢性疼痛是指超过正常愈合时间(一般指3个月)持续存在的自觉疼痛感,相对于急性疼痛而言,慢性疼痛一般会涉及生理或神经系统,并可能会影响身体的多个方面。由于受到发病机制复杂、个体差异大以及神经可塑性等因素的影响,慢性疼痛的治疗难度相对较大。药物治疗是慢性疼痛管理中的常用手段,关于药物的选择或配伍也一直是临床研究的热点。本文综述了钙离子通道阻滞剂在慢性疼痛中的应用,旨在为疾病的治疗提供参考。Modern medicine classifies pain as the fifth vital sign after respiration,pulse,blood pressure and body temperature,which shows its importance in human health.Chronic pain refers to the perceived pain that persists beyond the normal healing time(usually 3 months).In contrast to acute pain,chronic pain generally involves the physical or nervous system and may affect multiple aspects of the body.Due to the complex pathogenesis,individual differences and neuroplasticity,chronic pain is relatively difficult to treat.Drug therapy is a common method in chronic pain management,and the selection or compatibility of drugs has always been a hot spot in clinical research.This article reviews the application of calcium channel blockers in chronic pain,aiming to provide reference for the treatment of the disease.

关 键 词：慢性疼痛 钙离子通道阻滞剂 研究进展 

分 类 号：R59[医药卫生—内科学]