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作 者:古利群 鲍荣幸 古晓林 何海林 宋亚敏 臧鑫 GU Liqun;BAO Rongxing;GU Xiaolin;HE Hailin;SONG Yamin;ZANG Xin(Department of Cardiothoracic Intensive Care,Southern Medical University Affiliated Guangdong Provincial People's Hospital(Guangdong Academy of Medical Sciences),Guangzhou,Guangdong 510080,China)
机构地区:[1]南方医科大学附属广东省人民医院<广东省医学科学院>心外重症监护一科,广东广州510080
出 处:《医药前沿》2024年第12期20-24,共5页Journal of Frontiers of Medicine
摘 要:目的:分析成人心脏术后血管活性药物的使用量与术后重症监护时间延长的相关性。方法:收集2019年1—6月南方医科大学附属广东省人民医院442例接受心脏手术的成人患者的临床数据,根据血管活性药物评分将患者分低值组(0~<5分)162例、中值组(5~<10分)201例和高值组(≥10分)79例。通过单因素和多因素Logistic回归分析术后血管活性药物使用量对重症监护时间的影响。结果:多因素Logistic回归分析提示,血管活性药物评分水平每增加1,术后发生重症监护时间延长的风险增加12%(OR=1.12,P<0.01),以血管活性药物评分低值组作为参照,高值组发生重症监护延长的概率是低值组的5.07倍(OR=5.07,P<0.01)。结论:成人心脏术后大剂量血管活性药物的使用会增加重症监护时间,且血管活性药物评分越高,影响越大。在术后应积极监测及合理使用血管活性药物,改善心脏术后患者的预后。Objective To investigate the relationship between the use of vasoactive drμgs and the duration of intensive care after cardiac surgery in adults.Methods Retrospective collection of clinical data from 442 adult patients who underwent cardiac surgery at Southern Medical University Affiliated Guangdong Provincial People's Hospital from January to June 2019.Patients were divided into three groups based on vasoactive inotropic score:low-value group(0-<5 points,n=162),medium-value group(5-<10 points,n=201),and high-value group(≥10 points,n=79).Univariate and multivariate logistic regression analyses were performed to assess the impact of vasopressor use on ICU stay duration.Results Multivariate logistic regression analysis showed that for every 1 increase in vasoactive inotropic score level,the risk of prolonged intensive care after surgery increased by 12%(OR=1.12,P<0.01).Using the low vasoactive inotropic score group as a reference,the high value group had a 5.07 times higher probability of prolonged intensive care compared to the low value group(OR=5.07,P<0.01).Conclusions The use of large doses of vasoactive drμgs after cardiac surgery in adults can increase the duration of intensive care,and the higher the vasoactive drμg score,the greater the effect.Active monitoring and rational use of vasoactive drμgs should be done to improve the prognosis of patients after cardiac surgery.
关 键 词:血管活性药物评分 心脏术后 重症监护时间 血管活性药物
分 类 号:R541[医药卫生—心血管疾病]
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