用于肼检测的新型芘基荧光分子探针的合成与性能  

Synthesis and Properties of A Novel Pyrenyl Fluorescent Molecular Probe for Hydrazine Detection

作　　者：孙萌[1] 马杰[1] SUN Meng;MA Jie(School of Materials and Chemistry,University of Shanghai for Science and Technology,Shanghai 200000,China)

机构地区：[1]上海理工大学材料与化学学院,上海200000

出　　处：《广州化学》2024年第2期30-35,I0002,共7页Guangzhou Chemistry

基　　金：上海市自然基金(15ZR1428500)。

摘　　要：利用1-芘甲醛优良的荧光性质,将其作为母体进行基团修饰,经过^(1)H-NMR和HRMS对结构进行表征,证实成功构建了肼荧光分子探针PMIDO。在DMSO-H2O体系中,PMIDO只能显示弱的荧光;在加入肼后,在含水量70%的条件下,显示出强的蓝色荧光,呈现出开灯型的荧光探针特征,检出限可达1.41×10^(-7)mol/L。同时,该探针对肼的检测呈现出高选择性和稳定抗干扰性,适用于5~10的pH范围,并在30 s内完成响应。进一步阐述了其荧光检测机制,即与肼反应后生成腙,为反应型肼的荧光检测提供有益参考。Excessive hydrazine does great harm to the environment and organisms.Hydrazine fluorescent molecular probe PMIDO was successfully constructed by using 1-pyrene formaldehyde as the parent,modified by groups,and characterized by^(1)H-NMR and HRMS.In the DMSO-H2O system,PMIDO can only show weak fluorescence.However,after the addition of hydrazine,at the water content of 70%,it showed strong blue fluorescence,showing the characteristics of fluorescent probe with light on,and the detection limit reached 1.41×10^(-7)mol/L.At the same time,the probe show high selectivity and stable anti-interference for the detection of hydrazine,suitable for the pH range of 5~10 systems,complete response within 30s.The fluorescence detection mechanism of probe PMIDO is described,that is,the reaction with hydrazine to from a hydrazone,which provides a useful reference for the fluorescence detection of reactive hydrazine.

关 键 词：肼 荧光分子探针 1-芘甲醛 反应型探针 腙 

分 类 号：O625.6[理学—有机化学] TB34[理学—化学]