穴位埋线结合降糖药对糖尿病患者胰高血糖素样肽-1水平的影响  

Effect of acupoint catgut embedding combined with antidiabetic drugs on glucagon-like peptide-1level in diabetic patients

作　　者：张璐[1] 范丹[1] 岳珊 马界 ZHANG Lu;FAN Dan;YUE Shan(Institute of Traditional Chinese Medicine,Sichuan Academy of Chinese Medicine,Chengdu Sichuan 610031,China)

机构地区：[1]四川省中医药科学院中医药研究所,四川成都610031

出　　处：《四川中医》2024年第1期178-181,共4页Journal of Sichuan of Traditional Chinese Medicine

基　　金：四川省科技厅基本科研项目(编号:2020JDKY0031)。

摘　　要：目的:探讨穴位埋线结合降糖药对糖尿病患者胰高血糖素样肽-1(GLP-1)水平的影响。方法:将74例糖尿病病患者随机分为降糖药加穴位埋线组、穴位埋线组和降糖药组3组,观察患者的胰高血糖素样肽-1(GLP-1)水平变化。结果:降糖药加穴位埋线组患者的胰高血糖素样肽-1(GLP-1)水平治疗前后对比有统计学意义(P<0.05),且治疗后降糖药加穴位埋线组与穴位埋线组、降糖药组比较差异均有统计学意义(P<0.05)。通过观察对比三组糖尿病患者治疗前后GLP-1水平,评判治疗效果,降糖药加穴位埋线组有效率92.00%,穴位埋线组有效率66.67%,降糖药组有效率80.00%。降糖药加穴位埋线组有效率高于穴位埋线组、降糖药组,且有统计学意义(P<0.05)。结论:穴位埋线结合降糖药对糖尿病具有显著临床疗效。这可能是通过调节患者胰高血糖素样肽-1(GLP-1)的水平来实现的。Objective:To investigate the effect of acupoint catgut embedding combined with antidiabetic drugs on the level of glucagon-like peptide-1(GLP-1)in diabetic patients.Methods:74diabetic patients were randomly divided into three groups:antidiabetic drugs combined with acupoint catgut embedding group,acupoint catgut embedding group and antidiabetic drugs group,and the level of glucagon-like peptide-1(GLP-1)was observed.Results:The levels of glucagon-like peptide-1(GLP-1)in the antidiabetic drugs combined with acupoint catgut embedding group has a statistically significant difference before and after treatment(P<0.05),and there were statistically significant differences between the antidiabetic drugs combined with acupoint catgut embedding group,acupoint catgut embedding group and antidiabetic drugs group after treatment(P<0.05).By comparing the levels of GLP-1in the three groups of diabetes patients before and after treatment,the treatment effect was evaluated.The effective rate of the antidiabetic drugs combined with acupoint catgut embedding group was 92.00%,the effective rate of the acupoint catgut embedding group was 66.67%,and the effective rate of the antidiabetic drugs group was 80.00%.The effective rate of the antidiabetic drugs combined with acupoint catgut embedding group was higher than the acupoint catgut embedding group and the antidiabetic drugs group,with statistical significance(P<0.05).Conclusion:Acupoint catgut embedding combined with antidiabetic drugs has significant clinical effect on diabetes.This may be achieved by regulating patients'levels of glucagon-like peptide-1(GLP-1).

关 键 词：穴位埋线 降糖药 糖尿病 胰高血糖素样肽-1 

分 类 号：R245.91[医药卫生—针灸推拿学] R587.1[医药卫生—中医临床基础]